Rescue of the MERTK phagocytic defect in a human iPSC disease model using translational read-through inducing drugs

Inherited retinal dystrophies are an important cause of blindness, for which currently there are no effective treatments. In order to study this heterogeneous group of diseases, adequate disease models are required in order to better understand pathology and to test potential therapies. Induced plur...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Ramsden, Conor M., Nommiste, Britta, R. Lane, Amelia, Carr, Amanda-Jayne F., Powner, Michael B., J. K. Smart, Matthew, Chen, Li Li, Muthiah, Manickam N., Webster, Andrew R., Moore, Anthony T., Cheetham, Michael E., da Cruz, Lyndon, Coffey, Peter J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427915/
https://ncbi.nlm.nih.gov/pubmed/28246391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00142-7
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