Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction

Age-related macular degeneration is the most common form of legal blindness in westernized societies, and polymorphisms in the gene encoding complement factor H (CFH) are associated with susceptibility to age-related macular degeneration in more than half of affected individuals. To investigate the...

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Detalhes bibliográficos
Main Authors: Coffey, Peter J., Gias, Carlos, McDermott, Caroline J., Lundh, Peter, Pickering, Matthew C., Sethi, Charanjit, Bird, Alan, Fitzke, Fred W., Maass, Annelie, Chen, Li Li, Holder, Graham E., Luthert, Philip J., Salt, Thomas E., Moss, Stephen E., Greenwood, John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034255/
https://ncbi.nlm.nih.gov/pubmed/17921253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705079104
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