Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction

Age-related macular degeneration is the most common form of legal blindness in westernized societies, and polymorphisms in the gene encoding complement factor H (CFH) are associated with susceptibility to age-related macular degeneration in more than half of affected individuals. To investigate the...

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Détails bibliographiques
Auteurs principaux: Coffey, Peter J., Gias, Carlos, McDermott, Caroline J., Lundh, Peter, Pickering, Matthew C., Sethi, Charanjit, Bird, Alan, Fitzke, Fred W., Maass, Annelie, Chen, Li Li, Holder, Graham E., Luthert, Philip J., Salt, Thomas E., Moss, Stephen E., Greenwood, John
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034255/
https://ncbi.nlm.nih.gov/pubmed/17921253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705079104
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