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Functional Evaluation of AMD-Associated Risk Variants of Complement Factor B

PURPOSE: The 32W and 32Q variants of complement factor B (CFB) are associated with reduced risk of developing neovascular age-related macular degeneration (AMD) compared with the common 32R allele. The objective of this study was to determine if the most protective R32Q variant affects the neovascul...

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Detaylı Bibliyografya
Yayımlandı:Invest Ophthalmol Vis Sci
Asıl Yazarlar: Pilotti, Camilla, Greenwood, John, Moss, Stephen E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Association for Research in Vision and Ophthalmology 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7405614/
https://ncbi.nlm.nih.gov/pubmed/32407521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.5.19
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