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Retinal Changes Precede Visual Dysfunction in the Complement Factor H Knockout Mouse

We previously reported that aged mice lacking complement factor H (CFH) exhibit visual defects and structural changes in the retina. However, it is not known whether this phenotype is age-related or is the consequence of disturbed development. To address this question we investigated the effect of C...

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Detalhes bibliográficos
Main Authors: Williams, Jennifer A. E., Greenwood, John, Moss, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699560/
https://ncbi.nlm.nih.gov/pubmed/23844226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068616
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