Fetal Hemoglobin in Sickle Cell Anemia: Molecular Characterization of the Unusually High Fetal Hemoglobin Phenotype in African Americans

par Akinsheye, Idowu, Solovieff, Nadia, Ngo, Duyen, Malek, Anita, Sebastiani, Paola, Steinberg, Martin H., Chui, David H.K.
Publié 2011

Therapeutic γ-globin inducers reduce transcriptional repression in hemoglobinopathy erythroid progenitors through distinct mechanisms

par Dai, Yan, Sangerman, Jose, Hong, Yuan Luo, Fuchareon, Suthat, Chui, David H.K., Faller, Douglas V., Perrine, Susan P.
Publié dans Blood Cells Mol Dis (2015)

The Genetics of Hemoglobin A(2) Regulation in Sickle Cell Anemia

par Griffin, Paula J., Sebastiani, Paola, Edward, Heather, Baldwin, Clinton T., Gladwin, Mark, Gordeuk, Victor, Chui, David H.K., Steinberg, Martin H.
Publié dans Am J Hematol (2014)

Imputation of missing genotypes: an empirical evaluation of IMPUTE

par Steinberg Martin H, Perls Thomas T, Fucharoen Supan, Chui David HK, Hartley Stephen W, Timofeev Nadia, Zhao Zhenming, Baldwin Clinton T, Sebastiani Paola
Publié 2008-12-01

Imputation of missing genotypes: an empirical evaluation of IMPUTE

par Zhao, Zhenming, Timofeev, Nadia, Hartley, Stephen W, Chui, David HK, Fucharoen, Supan, Perls, Thomas T, Steinberg, Martin H, Baldwin, Clinton T, Sebastiani, Paola
Publié 2008

A phase 2 study of HQK-1001, an oral fetal haemoglobin inducer, in β-thalassaemia intermedia

par Inati, Adlette, Kahale, Mario, Perrine, Susan P., Chui, David H.K., Taher, Ali T., Koussa, Suzanne, Abi Nasr, Therese, Abbas, Hussein, Ghalie, Richard G.
Publié 2013

A Long Noncoding RNA from the HBS1L-MYB Intergenic Region on Chr6q23 Regulates Human Fetal Hemoglobin Expression

par Morrison, Tasha A., Wilcox, Ibifiri, Luo, Hong-Yuan, Farrell, John J., Kurita, Ryo, Nakamura, Yukio, Murphy, George J., Cui, Shuaiying, Steinberg, Martin H., Chui, David H.K.
Publié dans Blood Cells Mol Dis (2017)

Sickle Cell Disease in Saudi Arabia: The Phenotype in Adults with the Arab-Indian Haplotype is not Benign

par Alsultan, Abdulrahman, Alabdulaali, Mohammed K., Griffin, Paula J., AlSuliman, Ahmed M., Ghabbour, Hazem A., Sebastiani, Paola, Albuali, Waleed H., Al-Ali, Amein K., Chui, David H.K., Steinberg, Martin H.
Publié 2013

A phased SNP-based classification of sickle cell anemia HBB haplotypes

par Shaikho, Elmutaz M., Farrell, John J., Alsultan, Abdulrahman, Qutub, Hatem, Al-Ali, Amein K., Figueiredo, Maria Stella, Chui, David H.K., Farrer, Lindsay A., Murphy, George J., Mostoslavsky, Gustavo, Sebastiani, Paola, Steinberg, Martin H.
Publié dans BMC Genomics (2017)

BCL11A IS A MAJOR HbF QUANTITATIVE TRAIT LOCUS IN THREE DIFFERENT POPULATIONS WITH β-HEMOGLOBINOPATHIES

par Sedgewick, Amanda E., Timofeev, Nadia, Sebastiani, Paola, So, Jason C.C., Ma, Edmond S.K., Chan, Li Chong, Fucharoen, Goonnapa, Fucharoen, Supan, Barbosa, Cynara G., Vardarajan, Badri N., Farrer, Lindsay A., Baldwin, Clinton T., Steinberg, Martin H., Chui, David H.K.
Publié 2008

A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells

par Park, Seonmi, Gianotti-Sommer, Andreia, Molina-Estevez, Francisco Javier, Vanuytsel, Kim, Skvir, Nick, Leung, Amy, Rozelle, Sarah S., Shaikho, Elmutaz Mohammed, Weir, Isabelle, Jiang, Zhihua, Luo, Hong-Yuan, Chui, David H.K., Figueiredo, Maria Stella, Alsultan, Abdulraham, Al-Ali, Amein, Sebastiani, Paola, Steinberg, Martin H., Mostoslavsky, Gustavo, Murphy, George J.
Publié dans Stem Cell Reports (2017)

Variants of ZBTB7A (LRF) and its β-Globin Gene Cluster Binding Motifs in Sickle Cell Anemia: —ZBTB7A and Sickle Cell Anemia—

par Shaikho, Elmutaz M., Habara, Alawi H., Alsultan, Abdulrahman, Al-Rubaish, A.M., Al-Muhanna, Fahad, Naserullah, Z., Alsuliman, A., Qutub, Hatem O., Patra, P.K., Sebastiani, Paola, Baltrusaitis, Kristin, Farrell, John J., Jiang, Zhihua, Luo, Hong-yuan, Chui, David H.K., Al-Ali, Amein K., Steinberg, Martin H.
Publié dans Blood Cells Mol Dis (2016)

Fetal Hemoglobin in Sickle Cell Anemia: Genetic Studies of the Arab-Indian Haplotype

par Ngo, Duyen, Bae, Harold, Steinberg, Martin H., Sebastiani, Paola, Solovieff, Nadia, Baldwin, Clinton T., Melista, Efthymia, Safaya, Surinder, Farrar, Lindsay A., Suliman, Ahmed M., Albuali, Waleed H., Al Bagshi, Muneer H., Akinsheye, Idowu, Gallagher, Patrick, Luo, Hong-yuan, Chui, David H.K., Farrell, John J., Al-Ali, Amein K., Alsultan, Abdulrahman
Publié 2013

A Candidate Trans-acting Modulator of Fetal Hemoglobin Gene Expression in the Arab-Indian Haplotype of Sickle Cell Anemia: —ANTXR1 Variants and HbF—

par Vathipadiekal, Vinod, Farrell, John J., Wang, Shuai, Edward, Heather L., Shappell, Heather, Al-Rubaish, A.M., Al-Muhanna, Fahad, Naserullah, Z., Alsuliman, A., Qutub, Hatem Othman, Simkin, Irene, Farrer, Lindsay A., Jiang, Zhihua, Luo, Hong-Yuan, Huang, Shengwen, Mostoslavsky, Gustavo, Murphy, George J., Patra, Pradeep.K., Chui, David H.K., Alsultan, Abdulrahman, Al-Ali, Amein K., Sebastiani, Paola., Steinberg, Martin. H.
Publié dans Am J Hematol (2016)