SUBSTRATE-DEPENDENT EFFECTS OF HUMAN ABCB1 CODING POLYMORPHISMS

per Gow, Jason M., Hodges, Laura M., Chinn, Leslie W., Kroetz, Deanna L.
Publicat 2008

Evolutionary Conservation of Vertebrate Blood–Brain Barrier Chemoprotective Mechanisms in Drosophila

per Mayer, Fahima, Mayer, Nasima, Chinn, Leslie, Pinsonneault, Robert L., Kroetz, Deanna, Bainton, Roland J.
Publicat 2009

Complex DDI by Fenebrutinib and the Use of Transporter Endogenous Biomarkers to Elucidate the Mechanism of DDI

per Jones, Nicholas S., Yoshida, Kenta, Salphati, Laurent, Kenny, Jane R., Durk, Matthew R., Chinn, Leslie W.
Publicat a Clin Pharmacol Ther (2019)

Steady State Bioequivalence of Generic and Innovator Formulations of Stavudine, Lamivudine, and Nevirapine in HIV-Infected Ugandan Adults

per Byakika-Tusiime, Jayne, Chinn, Leslie W., Oyugi, Jessica H., Obua, Celestino, Bangsberg, David R., Kroetz, Deanna L.
Publicat 2008

Population Pharmacokinetics, Efficacy Exposure-response Analysis, and Model-based Meta-analysis of Fenebrutinib in Subjects with Rheumatoid Arthritis

per Chan, Phyllis, Yu, Jiajie, Chinn, Leslie, Prohn, Marita, Huisman, Jan, Matzuka, Brett, Hanley, William, Tuckwell, Katie, Quartino, Angelica
Publicat a Pharm Res (2020)

Correction to: Population Pharmacokinetics, Efficacy Exposure-response Analysis, and Model-based Meta-analysis of Fenebrutinib in Subjects with Rheumatoid Arthritis

per Chan, Phyllis, Yu, Jiajie, Chinn, Leslie, Prohn, Marita, Huisman, Jan, Matzuka, Brett, Hanley, William, Tuckwell, Katie, Quartino, Angelica
Publicat a Pharm Res (2020)

Measuring the Overall Genetic Component of Nevirapine Pharmacokinetics and the Role of Selected Polymorphisms: Towards Addressing the Missing Heritability in Pharmacogenetic Phenot...

per Micheli, Janine E., Chinn, Leslie W., Shugarts, Sarah B., Patel, Ashish, Martin, Jeffrey N., Bangsberg, David R., Kroetz, Deanna L.
Publicat 2013

Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein)

per Hodges, Laura M., Markova, Svetlana M., Chinn, Leslie W., Gow, Jason M., Kroetz, Deanna L., Klein, Teri E., Altman, Russ B.
Publicat 2011

Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains

per Kelly, Libusha, Fukushima, Hisayo, Karchin, Rachel, Gow, Jason M, Chinn, Leslie W, Pieper, Ursula, Segal, Mark R, Kroetz, Deanna L, Sali, Andrej
Publicat 2010

Response to “Predictable difficulty or difficulty to predict”

per Kelly, Libusha, Fukushima, Hisayo, Karchin, Rachel, Gow, Jason M, Chinn, Leslie W, Pieper, Ursula, Segal, Mark R, Kroetz, Deanna L, Sali, Andrej
Publicat 2011

Physiologically‐Based Pharmacokinetic Model‐Informed Drug Development for Fenebrutinib: Understanding Complex Drug‐Drug Interactions

per Chen, Yuan, Ma, Fang, Jones, Nicholas S., Yoshida, Kenta, Chiang, Po‐Chang, Durk, Matthew R., Wright, Matthew R., Jin, Jin Yan, Chinn, Leslie W.
Publicat a CPT Pharmacometrics Syst Pharmacol (2020)

Understanding the Effect of Hydroxypropyl‐β‐Cyclodextrin on Fenebrutinib Absorption in an Itraconazole–Fenebrutinib Drug–Drug Interaction Study

per Durk, Matthew R., Jones, Nicholas S., Liu, Jia, Nagapudi, Karthik, Mao, Chen, Plise, Emile G., Wong, Susan, Chen, Jacob Z., Chen, Yuan, Chinn, Leslie W., Chiang, Po‐Chang
Publicat a Clin Pharmacol Ther (2020)

THE HUMAN MULTIDRUG RESISTANCE PROTEIN 4 (MRP4, ABCC4): FUNCTIONAL ANALYSIS OF A HIGHLY POLYMORPHIC GENE

per Abla, Nada, Chinn, Leslie W., Nakamura, Tsutomu, Liu, Li, Huang, Conrad C., Johns, Susan J., Kawamoto, Michiko, Stryke, Doug, Taylor, Travis R., Ferrin, Thomas E., Giacomini, Kathleen M., Kroetz, Deanna L.
Publicat 2008

Antibody-mediated activation of the FGFR1/Klothoβ complex corrects metabolic dysfunction and alters food preference in obese humans

per Baruch, Amos, Wong, Chin, Chinn, Leslie W., Vaze, Anjali, Sonoda, Junichiro, Gelzleichter, Thomas, Chen, Shan, Lewin-Koh, Nicholas, Morrow, Linda, Dheerendra, Suresh, Boismenu, Richard, Gutierrez, Johnny, Wakshull, Eric, Wilson, Maria E., Arora, Puneet S.
Publicat a Proc Natl Acad Sci U S A (2020)

Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression

per Hendrickson, Sher L., Lautenberger, James A., Chinn, Leslie Wei, Malasky, Michael, Sezgin, Efe, Kingsley, Lawrence A., Goedert, James J., Kirk, Gregory D., Gomperts, Edward D., Buchbinder, Susan P., Troyer, Jennifer L., O'Brien, Stephen J.
Publicat 2010

Genetic Associations of Variants in Genes Encoding HIV-Dependency Factors Required for HIV-1 Infection

per Chinn, Leslie W., Tang, Minzhong, Kessing, Bailey D., Lautenberger, James A., Troyer, Jennifer L., Malasky, Michael J., McIntosh, Carl, Kirk, Gregory D., Wolinsky, Steven M., Buchbinder, Susan P., Gomperts, Edward D., Goedert, James J., O'Brien, Stephen J.
Publicat 2010

Genome-wide Association Study Implicates PARD3B-based AIDS Restriction

per Troyer, Jennifer L., Nelson, George W., Lautenberger, James A., Chinn, Leslie, McIntosh, Carl, Johnson, Randall C., Sezgin, Efe, Kessing, Bailey, Malasky, Michael, Hendrickson, Sher L., Li, Guan, Pontius, Joan, Tang, Minzhong, An, Ping, Winkler, Cheryl A., Limou, Sophie, Le Clerc, Sigrid, Delaneau, Olivier, Zagury, Jean-François, Schuitemaker, Hanneke, van Manen, Daniëlle, Bream, Jay H., Gomperts, Edward D., Buchbinder, Susan, Goedert, James J., Kirk, Gregory D., O'Brien, Stephen J.
Publicat 2011

Fenebrutinib Versus Placebo or Adalimumab in Rheumatoid Arthritis: A Randomized, Double‐Blind, Phase II Trial

per Cohen, Stanley, Tuckwell, Katie, Katsumoto, Tamiko R., Zhao, Rui, Galanter, Joshua, Lee, Chin, Rae, Julie, Toth, Balazs, Ramamoorthi, Nandhini, Hackney, Jason A., Berman, Alberto, Damjanov, Nemanja, Fedkov, Dmytro, Jeka, Slawomir, Chinn, Leslie W., Townsend, Michael J., Morimoto, Alyssa M., Genovese, Mark C., Berman, Alberto, Porto, Alejandro, Granel, Amelia, Asnal, Cecilia, Mysler, Eduardo Fabian, Testa, Gladys Alicia, Zamora, Jose Luis Velasco, Moreno, Jose Luis Cristian, Gulin, Juan Pablo, Hofman, Julio, Ulla, Maria Rosa, Sabelli, Mirtha, Mannucci, Pablo Alejandro, Maid, Pablo Jorge, Melazzi, Ana Cláudia Cauceglia, Scotton, Antônio Scafuto, Ximenes, Antônio Carlos, Funes, Elisete, Gimenez, Emerson Alves, Marcolino, Flora Maria D’Andrea, Neto, João Francisco Marques, Keiserman, Mauro Waldemar, Radominski, Sebastião Cézar, Lima, Sônia Maria Alvarenga Anti Loduca, Pavan, Thaís Rohde, Azevedo, Valderílio Feijó, Koleva, Aneliya, Toncheva, Antoaneta, Bichovska, Daniela, Ivanova, Delina, Penev, Dimitar, Dimitrov, Emil, Mihaylova, Mariyana, Kapandjieva, Nadezhda, Marinova, Natalia, Aleksieva, Tanya, Tsvetanova, Tanya, Petranova, Tsvetanka, Popova, Valentina, Spasov, Yuliy, Toro, Carlos Enrique, Arteaga Unigarro, Carlos Ernesto, Jauregui, Edwin, Hernandez, Javier Dario Marquez, Raad, Juan Jose Jaller, Sanchez, Patricia Julieta Velez, Lee, Chang Keun, Suh, Chang‐Hee, Lee, Eun Young, Lee, Sang‐Heon, Kang, Seong Wook, Lee, Shin‐Seok, Lee, Yun Jong, Montiel, Beatriz Elena Zazueta, Pinzon de la O, Blanca Irma, Friedmann, Daniel Xibille, Lopez, Francisco Rosas, Torres, Isaura Rodriguez, Quezada, Luis Jara, Ceceña, Marco Maradiaga, Hernandez, Miguel Cortes, Salinas, Miguel Saavedra, Rapa, Agnieszka, Pawtel, Agnieszka, Zielinska, Agnieszka, Dudek, Anna, Rychlewska‐Hanczewska, Anna, Strzelecka, Anna, Racewicz, Artur, Stasiuk, Barbara, Gruszecka, Katarzyna, Dworak, Krystyna, Jeka, Slawomir, Lowenhoff, Tomasz, Maslyanskiy, Alexey, Rebrov, Andrey, Krechikova, Diana, Zhugrova, Elena, Shmidt, Evgeniya, Matsievskaya, Galina, Vinogradova, Irina, Ler, Irina, Eliseeva, Larisa, Savina, Ludmila, Stanislav, Marina, Sandin, Mikhail, Zyablova, Natalia, Korshunov, Nikolay, Mosesova, Nino, Polovnikova, Oksana, Nesmeyanova, Olga, Samigullina, Ruzana, Moiseev, Sergey, Noskov, Sergey, Raskina, Tatiana, Popova, Tatiana, Marchenko, Valeriy, Jovanovski, Aleksandar, Stamenkovic, Bojana, Ristic, Gorica, Lazarevic, Milijanka, Veselinovic, Mirjana, Vujasinovic‐Stupar, Nada, Damjanov, Nemanja, Ostojic, Predrag, Yagensky, Andriy, Gnylorybov, Andriy, Rekalov, Dmytro, Reshotko, Dmytroo, Fedkov, Dmytro, Dzyak, Georgiy, Gasanov, Iurii, Khimion, Ludmila, Stanislavchuk, Mykola, Prykhodko, Natalya, Nadashkevych, Oleg, Bortkevych, Oleg, Abrahamovych, Orest, Yatsyshyn, Roman, Turyanytsya, Samvel, Smiyan, Svitlana, Vizir, Vadym, Kachur, Victoria, Tseluyko, Vira, Povoroznyuk, Vladyslav, Koshlia, Volodymyr, Zhdan, Vyacheslav, Lymar, Yurii, Mostovoy, Yuriy, Hawkes, Angela, Mabaquiao, Arthur, Chu, Cong‐Qiu, Scoville, Craig, Wyatt, David, Weinstein, Debra, McIlwain, Harris, Vo, Jacqueline, Poiley, Jeffrey, Forstot, Joseph, Dao, Kathryn, Turner, Mark, Genovese, Mark, Borofsky, Michael, Caldron, Paul, Waller, Philip, Levin, Robert, Metyas, Samy, Stein, Scott, Shroff, Sharukh, Pang, Shirley, Cohen, Stanley, Syed, Tauseef, Chindalore, Vishala
Publicat a Arthritis Rheumatol (2020)