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Steady State Bioequivalence of Generic and Innovator Formulations of Stavudine, Lamivudine, and Nevirapine in HIV-Infected Ugandan Adults

BACKGROUND: Generic antiretroviral therapy is the mainstay of HIV treatment in resource-limited settings, yet there is little evidence confirming the bioequivalence of generic and brand name formulations. We compared the steady-state pharmacokinetics of lamivudine, stavudine and nevirapine in HIV-in...

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Main Authors: Byakika-Tusiime, Jayne, Chinn, Leslie W., Oyugi, Jessica H., Obua, Celestino, Bangsberg, David R., Kroetz, Deanna L.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602850/
https://ncbi.nlm.nih.gov/pubmed/19096711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003981
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