Structural Variants in SNCA Gene and the Implication to Synucleinopathies

le Chiba-Falek, Ornit
Foilsithe in Curr Opin Genet Dev (2017)

Towards precision medicine in Alzheimer’s disease: deciphering genetic data to establish informative biomarkers

le Chiba-Falek, Ornit, Lutz, Michael W.
Foilsithe in Expert Rev Precis Med Drug Dev (2017)

Probing the role of PPARγ in the regulation of late-onset Alzheimer’s disease-associated genes

le Barrera, Julio, Subramanian, Shobana, Chiba-Falek, Ornit
Foilsithe in PLoS One (2018)

Sex-dependent effect of APOE on Alzheimer's disease and other age-related neurodegenerative disorders

le Gamache, Julia, Yun, Young, Chiba-Falek, Ornit
Foilsithe in Dis Model Mech (2020)

APOE: The New Frontier in the Development of a Therapeutic Target towards Precision Medicine in Late-Onset Alzheimer’s

le Yang, Anna, Kantor, Boris, Chiba-Falek, Ornit
Foilsithe in Int J Mol Sci (2021)

Multiplication of the SNCA locus exacerbates neuronal nuclear aging

le Tagliafierro, Lidia, Zamora, Madison Elena, Chiba-Falek, Ornit
Foilsithe in Hum Mol Genet (2019)

Bioinformatics strategy to advance the interpretation of Alzheimer’s disease GWAS discoveries: the roads from association to causation

le Lutz, Michael W., Sprague, Daniel, Chiba-Falek, Ornit
Foilsithe in Alzheimers Dement (2019)

The effects of the TOMM40 poly-T alleles on Alzheimer’s disease phenotypes

le Chiba-Falek, Ornit, Gottschalk, William K., Lutz, Michael W.
Foilsithe in Alzheimers Dement (2018)

Good problems to have? Policy and societal implications of a disease-modifying therapy for presymptomatic late-onset Alzheimer’s disease

le Angrist, Misha, Yang, Anna, Kantor, Boris, Chiba-Falek, Ornit
Foilsithe in Life Sci Soc Policy (2020)

Gene Expression Analysis of Neurons and Astrocytes Isolated by Laser Capture Microdissection from Frozen Human Brain Tissues

le Tagliafierro, Lidia, Bonawitz, Kirsten, Glenn, Omolara C., Chiba-Falek, Ornit
Foilsithe in Front Mol Neurosci (2016)

Shared genetic etiology underlying Alzheimer’s disease and major depressive disorder

le Lutz, Michael W., Sprague, Daniel, Barrera, Julio, Chiba-Falek, Ornit
Foilsithe in Transl Psychiatry (2020)

Gene-Editing Technologies Paired With Viral Vectors for Translational Research Into Neurodegenerative Diseases

le Rittiner, Joseph Edward, Moncalvo, Malik, Chiba-Falek, Ornit, Kantor, Boris
Foilsithe in Front Mol Neurosci (2020)

The Role of Upregulated APOE in Alzheimer’s Disease Etiology

le Gottschalk, William K, Mihovilovic, Mirta, Roses, Allen D, Chiba-Falek, Ornit
Foilsithe in J Alzheimers Dis Parkinsonism (2016)

Shared Genetic Etiology Underlying Late-Onset Alzheimer’s Disease and Post Traumatic Stress Syndrome

le Lutz, Michael W., Luo, Sheng, Williamson, Douglas E., Chiba-Falek, Ornit
Foilsithe in Alzheimers Dement (2020)

The Path to Progress Preclinical Studies of Age-Related Neurodegenerative Diseases: A Perspective on Rodent and hiPSC-Derived Models

le MacDougall, Gabriella, Brown, Logan Y., Kantor, Boris, Chiba-Falek, Ornit
Foilsithe in Mol Ther (2021)

Regulation of α-Synuclein Expression by Poly (ADP Ribose) Polymerase-1 (PARP-1) Binding to the NACP-Rep1 Polymorphic Site Upstream of the SNCA Gene

le Chiba-Falek, Ornit, Kowalak, Jeffrey A., Smulson, Mark E., Nussbaum, Robert L.
Foilsithe 2005

The SSV evaluation system: a tool to prioritize short structural variants for studies of possible regulatory and causal variants

le Saul, Robert, Lutz, Michael W., Burns, Daniel K., Roses, Allen D., Chiba-Falek, Ornit
Foilsithe in Hum Mutat (2016)

The effects of PPARγ on the regulation of the TOMM40-APOE-C1 genes cluster

le Subramanian, Shobana, Gottschalk, William K., Kim, So Young, Roses, Allen D., Chiba-Falek, Ornit
Foilsithe in Biochim Biophys Acta (2017)

Interpreting Gene Expression Effects of Disease-Associated Variants: A Lesson from SNCA rs356168

le Glenn, Omolara-Chinue, Tagliafierro, Lidia, Beach, Thomas G., Woltjer, Randy L., Chiba-Falek, Ornit
Foilsithe in Front Genet (2017)

A CT-rich haplotype in intron 4 of SNCA confers risk for Lewy body pathology in Alzheimer’s disease and affects SNCA expression

le Lutz, Michael W., Saul, Robert, Linnertz, Colton, Glenn, Omolara-Chinue, Roses, Allen D., Chiba-Falek, Ornit
Foilsithe in Alzheimers Dement (2015)