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APOE: The New Frontier in the Development of a Therapeutic Target towards Precision Medicine in Late-Onset Alzheimer’s

Alzheimer’s disease (AD) has a critical unmet medical need. The consensus around the amyloid cascade hypothesis has been guiding pre-clinical and clinical research to focus mainly on targeting beta-amyloid for treating AD. Nevertheless, the vast majority of the clinical trials have repeatedly failed...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yang, Anna, Kantor, Boris, Chiba-Falek, Ornit
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865856/
https://ncbi.nlm.nih.gov/pubmed/33513969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031244
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