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APOE: The New Frontier in the Development of a Therapeutic Target towards Precision Medicine in Late-Onset Alzheimer’s

Alzheimer’s disease (AD) has a critical unmet medical need. The consensus around the amyloid cascade hypothesis has been guiding pre-clinical and clinical research to focus mainly on targeting beta-amyloid for treating AD. Nevertheless, the vast majority of the clinical trials have repeatedly failed...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Yang, Anna, Kantor, Boris, Chiba-Falek, Ornit
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865856/
https://ncbi.nlm.nih.gov/pubmed/33513969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031244
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