The Path to Progress Preclinical Studies of Age-Related Neurodegenerative Diseases: A Perspective on Rodent and hiPSC-Derived Models

Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most prevalent age-related neurodegenerative diseases, and currently no effective clinical treatments exist for either, despite decades of clinical trials. The failure to translate preclinical findings into effective treatments is ind...

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Bibliographic Details
Published in:Mol Ther
Main Authors: MacDougall, Gabriella, Brown, Logan Y., Kantor, Boris, Chiba-Falek, Ornit
Format: Artigo
Language:Inglês
Published: American Society of Gene & Cell Therapy 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934639/
https://ncbi.nlm.nih.gov/pubmed/33429080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2021.01.001
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