The Path to Progress Preclinical Studies of Age-Related Neurodegenerative Diseases: A Perspective on Rodent and hiPSC-Derived Models

Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most prevalent age-related neurodegenerative diseases, and currently no effective clinical treatments exist for either, despite decades of clinical trials. The failure to translate preclinical findings into effective treatments is ind...

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Dettagli Bibliografici
Pubblicato in:Mol Ther
Autori principali: MacDougall, Gabriella, Brown, Logan Y., Kantor, Boris, Chiba-Falek, Ornit
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2021
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934639/
https://ncbi.nlm.nih.gov/pubmed/33429080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2021.01.001
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