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Bioinformatics strategy to advance the interpretation of Alzheimer’s disease GWAS discoveries: the roads from association to causation
INTRODUCTION: Genome-wide-association studies (GWAS) discovered multiple late-onset Alzheimer’s disease (LOAD)-associated SNPs and inferred the genes based on proximity, however, the actual causal genes are yet to be identified. METHODS: We defined LOAD-GWAS regions by the most significantly associa...
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| Vydáno v: | Alzheimers Dement |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6699885/ https://ncbi.nlm.nih.gov/pubmed/31262699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2019.04.014 |
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