Noise exposure immediately activates cochlear mitogen-activated protein kinase signaling

Por Alagramam, Kumar N., Stepanyan, Ruben, Jamesdaniel, Samson, Chen, Daniel H.-C., Davis, Rickie R.
Publicado no Noise Health (2014)

Proteomics, bioinformatics and targeted gene expression analysis reveals up-regulation of cochlin and identifies other potential biomarkers in the mouse model for deafness in usher...

Por Chance, Mark R., Chang, Jinsook, Liu, Shuqing, Gokulrangan, Giridharan, Chen, Daniel H.-C., Lindsay, Aaron, Geng, Ruishuang, Zheng, Qing Y., Alagramam, Kumar
Publicado em 2010

Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein

Por Gopal, Suhasini R., Chen, Daniel H.-C., Chou, Shih-Wei, Zang, Jingjing, Neuhauss, Stephan C.F., Stepanyan, Ruben, McDermott, Brian M., Alagramam, Kumar N.
Publicado no J Neurosci (2015)

Modeling and Preventing Progressive Hearing Loss in Usher Syndrome III

Por Geng, Ruishuang, Omar, Akil, Gopal, Suhasini R., Chen, Daniel H.-C., Stepanyan, Ruben, Basch, Martin L., Dinculescu, Astra, Furness, David N., Saperstein, David, Hauswirth, William, Lustig, Lawrence R., Alagramam, Kumar N.
Publicado no Sci Rep (2017)

The Mechanosensory Structure of the Hair Cell Requires Clarin-1, a Protein Encoded by Usher Syndrome III Causative Gene

Por Geng, Ruishuang, Melki, Sami, Chen, Daniel H.-C., Tian, Guilian, Furness, David N., Oshima-Takago, Tomoko, Neef, Jakob, Moser, Tobias, Askew, Charles, Horwitz, Geoff, Holt, Jeffrey R., Imanishi, Yoshikazu, Alagramam, Kumar N.
Publicado em 2012

Noddy, a Mouse Harboring a Missense Mutation in Protocadherin-15, Reveals the Impact of Disrupting a Critical Interaction Site between Tip-Link Cadherins in Inner Ear Hair Cells

Por Geng, Ruishuang, Sotomayor, Marcos, Kinder, Kimberly J., Gopal, Suhasini R., Gerka-Stuyt, John, Chen, Daniel H.-C., Hardisty-Hughes, Rachel E., Ball, Greg, Parker, Andy, Gaudet, Rachelle, Furness, David, Brown, Steve D., Corey, David P., Alagramam, Kumar N.
Publicado em 2013

A small molecule mitigates hearing loss in a mouse model of Usher syndrome III

Por Alagramam, Kumar N., Gopal, Suhasini R., Geng, Ruishuang, Chen, Daniel H.-C., Nemet, Ina, Lee, Richard, Tian, Guilian, Miyagi, Masaru, Malagu, Karine F., Lock, Christopher J., Esmieu, William R. K., Owens, Andrew P., Lindsay, Nicola A., Ouwehand, Krista, Albertus, Faywell, Fischer, David F., Bürli, Roland W., MacLeod, Angus M., Harte, William E., Palczewski, Krzysztof, Imanishi, Yoshikazu
Publicado no Nat Chem Biol (2016)