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Proteomics, bioinformatics and targeted gene expression analysis reveals up-regulation of cochlin and identifies other potential biomarkers in the mouse model for deafness in usher syndrome type 1F

Proteins and protein networks associated with cochlear pathogenesis in the Ames waltzer (av) mouse, a model for deafness in Usher syndrome 1F (USH1F), were identified. Cochlear protein from wild-type and av mice at postnatal day 30, a time point in which cochlear pathology is well established, was a...

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Библиографические подробности
Главные авторы: Chance, Mark R., Chang, Jinsook, Liu, Shuqing, Gokulrangan, Giridharan, Chen, Daniel H.-C., Lindsay, Aaron, Geng, Ruishuang, Zheng, Qing Y., Alagramam, Kumar
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846161/
https://ncbi.nlm.nih.gov/pubmed/20097680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq025
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