The Mechanosensory Structure of the Hair Cell Requires Clarin-1, a Protein Encoded by Usher Syndrome III Causative Gene

Mutation in the clarin-1 gene (Clrn1) results in loss of hearing and vision in humans (Usher syndrome III), but the role of clarin-1 in the sensory hair cells is unknown. Clarin-1 is predicted to be a four transmembrane domain protein similar to members of the tetraspanin family. Mice carrying null...

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Detalhes bibliográficos
Main Authors: Geng, Ruishuang, Melki, Sami, Chen, Daniel H.-C., Tian, Guilian, Furness, David N., Oshima-Takago, Tomoko, Neef, Jakob, Moser, Tobias, Askew, Charles, Horwitz, Geoff, Holt, Jeffrey R., Imanishi, Yoshikazu, Alagramam, Kumar N.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422646/
https://ncbi.nlm.nih.gov/pubmed/22787034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0311-12.2012
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