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Disruption of Otoferlin Alters the Mode of Exocytosis at the Mouse Inner Hair Cell Ribbon Synapse
Sound encoding relies on Ca(2+)-mediated exocytosis at the ribbon synapse between cochlear inner hair cells (IHCs) and type I spiral ganglion neurons (SGNs). Otoferlin, a multi-C(2) domain protein, is proposed to regulate Ca(2+)-triggered exocytosis at this synapse, but the precise mechanisms of oto...
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| Publicado no: | Front Mol Neurosci |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6338019/ https://ncbi.nlm.nih.gov/pubmed/30687007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00492 |
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