A cylindrical assembly model and dynamics of the Ebola virus VP40 structural matrix

by Pavadai, Elumalai, Gerstman, Bernard S., Chapagain, Prem P.
Published in Sci Rep (2018)

Potential RNA-dependent RNA polymerase inhibitors as prospective therapeutics against SARS-CoV-2

by Pokhrel, Rudramani, Chapagain, Prem, Siltberg-Liberles, Jessica
Published in J Med Microbiol (2020)

Fluorescent protein barrel fluctuations and oxygen diffusion pathways in mCherry

by Chapagain, Prem P., Regmi, Chola K., Castillo, William
Published 2011

Direct observation of a 91 bp LacI-mediated, negatively supercoiled DNA loop by atomic force microscope

by Fulcrand, Geraldine, Chapagain, Prem, Dunlap, David, Leng, Fenfei
Published in FEBS Lett (2016)

Investigating molecular interactions between oxidized neuroglobin and cytochrome c

by Tiwari, Purushottam B., Chapagain, Prem P., Üren, Aykut
Published in Sci Rep (2018)

Discovery of novel bacterial topoisomerase I inhibitors by use of in silico docking and in vitro assays

by Sandhaus, Shayna, Chapagain, Prem P., Tse-Dinh, Yuk-Ching
Published in Sci Rep (2018)

In-silico identification of the vaccine candidate epitopes against the Lassa virus hemorrhagic fever

by Baral, Prabin, Pavadai, Elumalai, Gerstman, Bernard S., Chapagain, Prem P.
Published in Sci Rep (2020)

Exploring the Diffusion of Molecular Oxygen in the Red Fluorescent Protein mCherry Using Explicit Oxygen Molecular Dynamics Simulations

by Regmi, Chola K., Bhandari, Yuba R., Gerstman, Bernard S., Chapagain, Prem P.
Published 2013

The Ebola virus protein VP40 hexamer enhances the clustering of PI(4,5)P(2) lipids in the plasma membrane

by GC, Jeevan B., Gerstman, Bernard S., Stahelin, Robert V., Chapagain, Prem P.
Published in Phys Chem Chem Phys (2016)

Hydrogen Bond Flexibility Correlates with Stokes Shift in mPlum Variants

by Konold, Patrick, Regmi, Chola K., Chapagain, Prem P., Gerstman, Bernard S., Jimenez, Ralph
Published 2014

Plasma membrane association facilitates conformational changes in the Marburg virus protein VP40 dimer

by Bhattarai, Nisha, GC, Jeevan B., Gerstman, Bernard S., Stahelin, Robert V., Chapagain, Prem P.
Published in RSC Adv (2017)

DNA supercoiling, a critical signal regulating the basal expression of the lac operon in Escherichia coli

by Fulcrand, Geraldine, Dages, Samantha, Zhi, Xiaoduo, Chapagain, Prem, Gerstman, Bernard S., Dunlap, David, Leng, Fenfei
Published in Sci Rep (2016)

Conformational Flexibility of the Protein-Protein Interfaces of the Ebola Virus VP40 Structural Matrix Filament

by Pavadai, Elumalai, Bhattarai, Nisha, Baral, Prabin, Stahelin, Robert V., Chapagain, Prem P., Gerstman, Bernard S.
Published in J Phys Chem B (2019)

Exploring Structural and Optical Properties of Fluorescent Proteins by Squeezing: Modeling High-Pressure Effects on the mStrawberry and mCherry Red Fluorescent Proteins

by Laurent, Adele D., Mironov, Vladimir A., Chapagain, Prem P., Nemukhin, Alexander V., Krylov, Anna I.
Published 2012

Ca(2+) and Mg(2+) modulate conformational dynamics and stability of downstream regulatory element antagonist modulator

by Pham, Khoa, Dhulipala, Gangadhar, Gonzalez, Walter G, Gerstman, Bernard S, Regmi, Chola, Chapagain, Prem P, Miksovska, Jaroslava
Published in Protein Sci (2015)

Characterization of molecular interactions between E. coli RNA polymerase and topoisomerase I by molecular simulations

by Tiwari, Purushottam Babu, Chapagain, Prem P., Banda, Srikanth, Darici, Yesim, Üren, Aykut, Tse-Dinh, Yuk-Ching
Published in FEBS Lett (2016)

Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development

by Tiwari, Purushottam B., Chapagain, Prem P., Seddek, Ahmed, Annamalai, Thirunavukkarasu, Üren, Aykut, Tse-Dinh, Yuk-Ching
Published in ChemMedChem (2020)

A Conserved Tryptophan in the Ebola Virus Matrix Protein C-Terminal Domain Is Required for Efficient Virus-Like Particle Formation

by Johnson, Kristen A., Pokhrel, Rudramani, Budicini, Melissa R., Gerstman, Bernard S., Chapagain, Prem P., Stahelin, Robert V.
Published in Pathogens (2020)

Graphene-VP40 interactions and potential disruption of the Ebola virus matrix filaments

by GC, Jeevan B., Pokhrel, Rudramani, Bhattarai, Nisha, Johnson, Kristen A., Gerstman, Bernard S., Stahelin, Robert V., Chapagain, Prem P.
Published in Biochem Biophys Res Commun (2017)

The Integrin Binding Peptide, ATN-161, as a Novel Therapy for SARS-CoV-2 Infection

by Beddingfield, Brandon, Iwanaga, Naoki, Chapagain, Prem, Zheng, Wenshu, Roy, Chad J., Hu, Tony Y., Kolls, Jay, Bix, Gregory
Published in bioRxiv (2020)