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Exploring Structural and Optical Properties of Fluorescent Proteins by Squeezing: Modeling High-Pressure Effects on the mStrawberry and mCherry Red Fluorescent Proteins

Molecular dynamics calculations of pressure effects on mStrawberry and mCherry fluorescent proteins are reported. The simulations reveal that mStrawberry has much floppier structure at atmospheric pressure, as evidenced by larger backbone fluctuations and coexistence of two conformers which differ b...

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Detalhes bibliográficos
Main Authors: Laurent, Adele D., Mironov, Vladimir A., Chapagain, Prem P., Nemukhin, Alexander V., Krylov, Anna I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500579/
https://ncbi.nlm.nih.gov/pubmed/22988813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp3060944
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