Loading...
Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development
A topoisomerase-DNA transient covalent complex can be a druggable target for novel topoisomerase poison inhibitors that represent a new class of antibacterial or anticancer drugs. Herein, we have investigated molecular features of the functionally important Escherichia coli topoisomerase I (EctopoI)...
Saved in:
| Published in: | ChemMedChem |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2020
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7133791/ https://ncbi.nlm.nih.gov/pubmed/32043806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201900721 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|