A cylindrical assembly model and dynamics of the Ebola virus VP40 structural matrix

per Pavadai, Elumalai, Gerstman, Bernard S., Chapagain, Prem P.
Publicat a Sci Rep (2018)

Potential RNA-dependent RNA polymerase inhibitors as prospective therapeutics against SARS-CoV-2

per Pokhrel, Rudramani, Chapagain, Prem, Siltberg-Liberles, Jessica
Publicat a J Med Microbiol (2020)

Fluorescent protein barrel fluctuations and oxygen diffusion pathways in mCherry

per Chapagain, Prem P., Regmi, Chola K., Castillo, William
Publicat 2011

Direct observation of a 91 bp LacI-mediated, negatively supercoiled DNA loop by atomic force microscope

per Fulcrand, Geraldine, Chapagain, Prem, Dunlap, David, Leng, Fenfei
Publicat a FEBS Lett (2016)

Investigating molecular interactions between oxidized neuroglobin and cytochrome c

per Tiwari, Purushottam B., Chapagain, Prem P., Üren, Aykut
Publicat a Sci Rep (2018)

Discovery of novel bacterial topoisomerase I inhibitors by use of in silico docking and in vitro assays

per Sandhaus, Shayna, Chapagain, Prem P., Tse-Dinh, Yuk-Ching
Publicat a Sci Rep (2018)

In-silico identification of the vaccine candidate epitopes against the Lassa virus hemorrhagic fever

per Baral, Prabin, Pavadai, Elumalai, Gerstman, Bernard S., Chapagain, Prem P.
Publicat a Sci Rep (2020)

Exploring the Diffusion of Molecular Oxygen in the Red Fluorescent Protein mCherry Using Explicit Oxygen Molecular Dynamics Simulations

per Regmi, Chola K., Bhandari, Yuba R., Gerstman, Bernard S., Chapagain, Prem P.
Publicat 2013

The Ebola virus protein VP40 hexamer enhances the clustering of PI(4,5)P(2) lipids in the plasma membrane

per GC, Jeevan B., Gerstman, Bernard S., Stahelin, Robert V., Chapagain, Prem P.
Publicat a Phys Chem Chem Phys (2016)

Hydrogen Bond Flexibility Correlates with Stokes Shift in mPlum Variants

per Konold, Patrick, Regmi, Chola K., Chapagain, Prem P., Gerstman, Bernard S., Jimenez, Ralph
Publicat 2014

Plasma membrane association facilitates conformational changes in the Marburg virus protein VP40 dimer

per Bhattarai, Nisha, GC, Jeevan B., Gerstman, Bernard S., Stahelin, Robert V., Chapagain, Prem P.
Publicat a RSC Adv (2017)

DNA supercoiling, a critical signal regulating the basal expression of the lac operon in Escherichia coli

per Fulcrand, Geraldine, Dages, Samantha, Zhi, Xiaoduo, Chapagain, Prem, Gerstman, Bernard S., Dunlap, David, Leng, Fenfei
Publicat a Sci Rep (2016)

Conformational Flexibility of the Protein-Protein Interfaces of the Ebola Virus VP40 Structural Matrix Filament

per Pavadai, Elumalai, Bhattarai, Nisha, Baral, Prabin, Stahelin, Robert V., Chapagain, Prem P., Gerstman, Bernard S.
Publicat a J Phys Chem B (2019)

Exploring Structural and Optical Properties of Fluorescent Proteins by Squeezing: Modeling High-Pressure Effects on the mStrawberry and mCherry Red Fluorescent Proteins

per Laurent, Adele D., Mironov, Vladimir A., Chapagain, Prem P., Nemukhin, Alexander V., Krylov, Anna I.
Publicat 2012

Ca(2+) and Mg(2+) modulate conformational dynamics and stability of downstream regulatory element antagonist modulator

per Pham, Khoa, Dhulipala, Gangadhar, Gonzalez, Walter G, Gerstman, Bernard S, Regmi, Chola, Chapagain, Prem P, Miksovska, Jaroslava
Publicat a Protein Sci (2015)

Characterization of molecular interactions between E. coli RNA polymerase and topoisomerase I by molecular simulations

per Tiwari, Purushottam Babu, Chapagain, Prem P., Banda, Srikanth, Darici, Yesim, Üren, Aykut, Tse-Dinh, Yuk-Ching
Publicat a FEBS Lett (2016)

Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development

per Tiwari, Purushottam B., Chapagain, Prem P., Seddek, Ahmed, Annamalai, Thirunavukkarasu, Üren, Aykut, Tse-Dinh, Yuk-Ching
Publicat a ChemMedChem (2020)

A Conserved Tryptophan in the Ebola Virus Matrix Protein C-Terminal Domain Is Required for Efficient Virus-Like Particle Formation

per Johnson, Kristen A., Pokhrel, Rudramani, Budicini, Melissa R., Gerstman, Bernard S., Chapagain, Prem P., Stahelin, Robert V.
Publicat a Pathogens (2020)

Graphene-VP40 interactions and potential disruption of the Ebola virus matrix filaments

per GC, Jeevan B., Pokhrel, Rudramani, Bhattarai, Nisha, Johnson, Kristen A., Gerstman, Bernard S., Stahelin, Robert V., Chapagain, Prem P.
Publicat a Biochem Biophys Res Commun (2017)

The Integrin Binding Peptide, ATN-161, as a Novel Therapy for SARS-CoV-2 Infection

per Beddingfield, Brandon, Iwanaga, Naoki, Chapagain, Prem, Zheng, Wenshu, Roy, Chad J., Hu, Tony Y., Kolls, Jay, Bix, Gregory
Publicat a bioRxiv (2020)