Melanocortin receptor accessory proteins in adrenal disease and obesity

door Jackson, David S., Ramachandrappa, Shwetha, Clark, Adrian J., Chan, Li F.
Gepubliceerd in Front Neurosci (2015)

Overexpression of melanocortin 2 receptor accessory protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure

door Bruschetta, Giuseppe, Kim, Jung Dae, Diano, Sabrina, Chan, Li F.
Gepubliceerd in Mol Metab (2018)

The melanocortin receptors and their accessory proteins

door Ramachandrappa, Shwetha, Gorrigan, Rebecca J., Clark, Adrian J. L., Chan, Li F.
Gepubliceerd in 2013

Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland

door Gorrigan, Rebecca J, Guasti, Leonardo, King, Peter, Clark, Adrian J, Chan, Li F
Gepubliceerd in 2011

Phenotypic characteristics of familial glucocorticoid deficiency (FGD) type 1 and 2

door Chung, Teng-Teng L L, Chan, Li F, Metherell, Louise A, Clark, Adrian J L
Gepubliceerd in 2010

Functional consequence of a novel Y129C mutation in a patient with two contradictory melanocortin-2-receptor mutations

door Chan, Li F, Chung, Teng-Teng, Massoud, Ahmed F, Metherell, Louise A, Clark, Adrian J L
Gepubliceerd in 2009

Whole-Exome Sequencing in the Differential Diagnosis of Primary Adrenal Insufficiency in Children

door Chan, Li F., Campbell, Daniel C., Novoselova, Tatiana V., Clark, Adrian J. L., Metherell, Louise A.
Gepubliceerd in Front Endocrinol (Lausanne) (2015)

Diabetes and Obesity in Down Syndrome Across the Lifespan: A Retrospective Cohort Study Using U.K. Electronic Health Records

door Aslam, Aisha A., Baksh, R. Asaad, Pape, Sarah E., Strydom, Andre, Gulliford, Martin C., Chan, Li F.
Gepubliceerd in Diabetes Care (2022)

ACTH signalling and adrenal development: lessons from mouse models

door Novoselova, Tatiana V, King, Peter J, Guasti, Leonardo, Metherell, Louise A, Clark, Adrian J L, Chan, Li F
Gepubliceerd in Endocr Connect (2019)

MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation

door Novoselova, Tatiana V., Hussain, Mashal, King, Peter J., Guasti, Leonardo, Metherell, Louise A., Charalambous, Marika, Clark, Adrian J. L., Chan, Li F.
Gepubliceerd in FASEB J (2018)

NNT Pseudoexon Activation as a Novel Mechanism for Disease in Two Siblings With Familial Glucocorticoid Deficiency

door Novoselova, Tatiana V., Rath, Shoshana R., Carpenter, Karen, Pachter, Nicholas, Dickinson, Jan E., Price, Glynis, Chan, Li F., Choong, Catherine S., Metherell, Louise A.
Gepubliceerd in J Clin Endocrinol Metab (2015)

Homozygous nonsense and frameshift mutations of the ACTH receptor in children with familial glucocorticoid deficiency (FGD) are not associated with long-term mineralocorticoid defi...

door Chan, Li F, Metherell, Louise A, Krude, Heiko, Ball, Colin, O'Riordan, Stephen M P, Costigan, Colm, Lynch, Sally A, Savage, Martin O, Cavarzere, Paolo, Clark, Adrian J L
Gepubliceerd in 2009

Thioredoxin Reductase 2 (TXNRD2) Mutation Associated With Familial Glucocorticoid Deficiency (FGD)

door Prasad, Rathi, Chan, Li F., Hughes, Claire R., Kaski, Juan P., Kowalczyk, Julia C., Savage, Martin O., Peters, Catherine J., Nathwani, Nisha, Clark, Adrian J. L., Storr, Helen L., Metherell, Louise A.
Gepubliceerd in 2014

MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family

door Chan, Li F., Webb, Tom R., Chung, Teng-Teng, Meimaridou, Eirini, Cooray, Sadani N., Guasti, Leonardo, Chapple, J. Paul, Egertová, Michaela, Elphick, Maurice R., Cheetham, Michael E., Metherell, Louise A., Clark, Adrian J. L.
Gepubliceerd in 2009

Central role for melanocortin-4 receptors in offspring hypertension arising from maternal obesity

door Samuelsson, Anne-Maj S., Mullier, Amandine, Maicas, Nuria, Oosterhuis, Nynke R., Eun Bae, Sung, Novoselova, Tatiana V., Chan, Li F., Pombo, Joaquim M., Taylor, Paul D., Joles, Jaap A., Coen, Clive W., Balthasar, Nina, Poston, Lucilla
Gepubliceerd in Proc Natl Acad Sci U S A (2016)

Loss of Function of the Melanocortin 2 Receptor Accessory Protein 2 Is Associated with Mammalian Obesity

door Asai, Masato, Ramachandrappa, Shwetha, Joachim, Maria, Shen, Yuan, Zhang, Rong, Nuthalapati, Nikhil, Ramanathan, Visali, Strochlic, David E., Ferket, Peter, Linhart, Kirsten, Ho, Caroline, Novoselova, Tatiana V., Garg, Sumedha, Ridderstråle, Martin, Marcus, Claude, Hirschhorn, Joel N., Keogh, Julia M., O’Rahilly, Stephen, Chan, Li F., Clark, Adrian J., Farooqi, I. Sadaf, Majzoub, Joseph A.
Gepubliceerd in 2013

Genetic Analysis of Pediatric Primary Adrenal Insufficiency of Unknown Etiology: 25 Years’ Experience in the UK

door Buonocore, Federica, Maharaj, Avinaash, Qamar, Younus, Koehler, Katrin, Suntharalingham, Jenifer P, Chan, Li F, Ferraz-de-Souza, Bruno, Hughes, Claire R, Lin, Lin, Prasad, Rathi, Allgrove, Jeremy, Andrews, Edward T, Buchanan, Charles R, Cheetham, Tim D, Crowne, Elizabeth C, Davies, Justin H, Gregory, John W, Hindmarsh, Peter C, Hulse, Tony, Krone, Nils P, Shah, Pratik, Shaikh, M Guftar, Roberts, Catherine, Clayton, Peter E, Dattani, Mehul T, Thomas, N Simon, Huebner, Angela, Clark, Adrian J, Metherell, Louise A, Achermann, John C
Gepubliceerd in J Endocr Soc (2021)