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Overexpression of melanocortin 2 receptor accessory protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure

OBJECTIVE: Melanocortin 2 receptor accessory protein 2 (MRAP2) has a critical role in energy homeostasis. Although MRAP2 has been shown to regulates a number of GPCRs involved in metabolism, the key neurons responsible for the phenotype of gross obesity in MRAP2 deficient animals are unclear. Furthe...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Bruschetta, Giuseppe, Kim, Jung Dae, Diano, Sabrina, Chan, Li F.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6308034/
https://ncbi.nlm.nih.gov/pubmed/30352741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.09.010
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