Melanocortin receptor accessory proteins in adrenal disease and obesity

Por Jackson, David S., Ramachandrappa, Shwetha, Clark, Adrian J., Chan, Li F.
Publicado no Front Neurosci (2015)

Overexpression of melanocortin 2 receptor accessory protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure

Por Bruschetta, Giuseppe, Kim, Jung Dae, Diano, Sabrina, Chan, Li F.
Publicado no Mol Metab (2018)

The melanocortin receptors and their accessory proteins

Por Ramachandrappa, Shwetha, Gorrigan, Rebecca J., Clark, Adrian J. L., Chan, Li F.
Publicado em 2013

Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland

Por Gorrigan, Rebecca J, Guasti, Leonardo, King, Peter, Clark, Adrian J, Chan, Li F
Publicado em 2011

Phenotypic characteristics of familial glucocorticoid deficiency (FGD) type 1 and 2

Por Chung, Teng-Teng L L, Chan, Li F, Metherell, Louise A, Clark, Adrian J L
Publicado em 2010

Functional consequence of a novel Y129C mutation in a patient with two contradictory melanocortin-2-receptor mutations

Por Chan, Li F, Chung, Teng-Teng, Massoud, Ahmed F, Metherell, Louise A, Clark, Adrian J L
Publicado em 2009

Whole-Exome Sequencing in the Differential Diagnosis of Primary Adrenal Insufficiency in Children

Por Chan, Li F., Campbell, Daniel C., Novoselova, Tatiana V., Clark, Adrian J. L., Metherell, Louise A.
Publicado no Front Endocrinol (Lausanne) (2015)

Diabetes and Obesity in Down Syndrome Across the Lifespan: A Retrospective Cohort Study Using U.K. Electronic Health Records

Por Aslam, Aisha A., Baksh, R. Asaad, Pape, Sarah E., Strydom, Andre, Gulliford, Martin C., Chan, Li F.
Publicado no Diabetes Care (2022)

ACTH signalling and adrenal development: lessons from mouse models

Por Novoselova, Tatiana V, King, Peter J, Guasti, Leonardo, Metherell, Louise A, Clark, Adrian J L, Chan, Li F
Publicado no Endocr Connect (2019)

MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation

Por Novoselova, Tatiana V., Hussain, Mashal, King, Peter J., Guasti, Leonardo, Metherell, Louise A., Charalambous, Marika, Clark, Adrian J. L., Chan, Li F.
Publicado no FASEB J (2018)

NNT Pseudoexon Activation as a Novel Mechanism for Disease in Two Siblings With Familial Glucocorticoid Deficiency

Por Novoselova, Tatiana V., Rath, Shoshana R., Carpenter, Karen, Pachter, Nicholas, Dickinson, Jan E., Price, Glynis, Chan, Li F., Choong, Catherine S., Metherell, Louise A.
Publicado no J Clin Endocrinol Metab (2015)

Homozygous nonsense and frameshift mutations of the ACTH receptor in children with familial glucocorticoid deficiency (FGD) are not associated with long-term mineralocorticoid defi...

Por Chan, Li F, Metherell, Louise A, Krude, Heiko, Ball, Colin, O'Riordan, Stephen M P, Costigan, Colm, Lynch, Sally A, Savage, Martin O, Cavarzere, Paolo, Clark, Adrian J L
Publicado em 2009

Thioredoxin Reductase 2 (TXNRD2) Mutation Associated With Familial Glucocorticoid Deficiency (FGD)

Por Prasad, Rathi, Chan, Li F., Hughes, Claire R., Kaski, Juan P., Kowalczyk, Julia C., Savage, Martin O., Peters, Catherine J., Nathwani, Nisha, Clark, Adrian J. L., Storr, Helen L., Metherell, Louise A.
Publicado em 2014

MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family

Por Chan, Li F., Webb, Tom R., Chung, Teng-Teng, Meimaridou, Eirini, Cooray, Sadani N., Guasti, Leonardo, Chapple, J. Paul, Egertová, Michaela, Elphick, Maurice R., Cheetham, Michael E., Metherell, Louise A., Clark, Adrian J. L.
Publicado em 2009

Central role for melanocortin-4 receptors in offspring hypertension arising from maternal obesity

Por Samuelsson, Anne-Maj S., Mullier, Amandine, Maicas, Nuria, Oosterhuis, Nynke R., Eun Bae, Sung, Novoselova, Tatiana V., Chan, Li F., Pombo, Joaquim M., Taylor, Paul D., Joles, Jaap A., Coen, Clive W., Balthasar, Nina, Poston, Lucilla
Publicado no Proc Natl Acad Sci U S A (2016)

Loss of Function of the Melanocortin 2 Receptor Accessory Protein 2 Is Associated with Mammalian Obesity

Por Asai, Masato, Ramachandrappa, Shwetha, Joachim, Maria, Shen, Yuan, Zhang, Rong, Nuthalapati, Nikhil, Ramanathan, Visali, Strochlic, David E., Ferket, Peter, Linhart, Kirsten, Ho, Caroline, Novoselova, Tatiana V., Garg, Sumedha, Ridderstråle, Martin, Marcus, Claude, Hirschhorn, Joel N., Keogh, Julia M., O’Rahilly, Stephen, Chan, Li F., Clark, Adrian J., Farooqi, I. Sadaf, Majzoub, Joseph A.
Publicado em 2013