MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family

The melanocortin receptor (MCR) family consists of 5 G protein-coupled receptors (MC1R–MC5R) with diverse physiologic roles. MC2R is a critical component of the hypothalamic–pituitary–adrenal axis, whereas MC3R and MC4R have an essential role in energy homeostasis. Mutations in MC4R are the single m...

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Hoofdauteurs: Chan, Li F., Webb, Tom R., Chung, Teng-Teng, Meimaridou, Eirini, Cooray, Sadani N., Guasti, Leonardo, Chapple, J. Paul, Egertová, Michaela, Elphick, Maurice R., Cheetham, Michael E., Metherell, Louise A., Clark, Adrian J. L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2009
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661846/
https://ncbi.nlm.nih.gov/pubmed/19329486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809918106
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