Pharmacological and Functional Genetic Assays to Manipulate Regeneration of the Planarian Dugesia japonica

av Chan, John D., Marchant, Jonathan S.
Publicerad 2011

Anti-schistosomal action of the calcium channel agonist FPL-64176

av McCusker, Paul, Chan, John D.
I publikationen Int J Parasitol Drugs Drug Resist (2019)

Ca(2+) channels and Praziquantel: a view from the free world

av Chan, John D., Zarowiecki, Magdalena, Marchant, Jonathan S.
Publicerad 2012

Kinetic profiling an abundantly expressed planarian serotonergic GPCR identifies bromocriptine as a perdurant antagonist

av Chan, John D., Grab, Thomas, Marchant, Jonathan S.
I publikationen Int J Parasitol Drugs Drug Resist (2016)

Coalescing beneficial host and deleterious antiparasitic actions as an antischistosomal strategy

av Chan, John D, Day, Timothy A, Marchant, Jonathan S
I publikationen eLife (2018)

Structure-activity profiling of alkaloid natural product pharmacophores against a Schistosoma serotonin receptor

av Marchant, Jonathan S., Harding, Wayne W., Chan, John D.
I publikationen Int J Parasitol Drugs Drug Resist (2018)

A Novel Biological Activity of Praziquantel Requiring Voltage-Operated Ca(2+) Channel β Subunits: Subversion of Flatworm Regenerative Polarity

av Nogi, Taisaku, Zhang, Dan, Chan, John D., Marchant, Jonathan S.
Publicerad 2009

Opposing Roles of Voltage-Gated Ca(2+) Channels in Neuronal Control of Regenerative Patterning

av Zhang, Dan, Chan, John D., Nogi, Taisaku, Marchant, Jonathan S.
Publicerad 2011

Characterization of a flatworm inositol (1,4,5) trisphosphate receptor (IP(3)R) reveals a role in reproductive physiology

av Zhang, Dan, Liu, Xiaolong, Chan, John D., Marchant, Jonathan S.
Publicerad 2013

Schistosoma mansoni alter transcription of immunomodulatory gene products following in vivo praziquantel exposure

av McCusker, Paul, Rohr, Claudia M., Chan, John D.
I publikationen PLoS Negl Trop Dis (2021)

Pharmacological profiling an abundantly expressed schistosome serotonergic GPCR identifies nuciferine as a potent antagonist

av Chan, John D., Acharya, Sreemoyee, Day, Timothy A., Marchant, Jonathan S.
I publikationen Int J Parasitol Drugs Drug Resist (2016)

Making Heads or Tails: Planarian Stem Cells in the Classroom(†)

av Srougi, Melissa C., Thomas-Swanik, Jackie, Chan, John D., Marchant, Jonathan S., Carson, Susan
Publicerad 2014

Dataset for a Dugesia japonica de novo transcriptome assembly, utilized for defining the voltage-gated like ion channel superfamily

av Chan, John D., Zhang, Dan, Liu, Xiaolong, Zarowiecki, Magdalena Z., Berriman, Matthew, Marchant, Jonathan S.
I publikationen Data Brief (2016)

Utilizing the planarian voltage-gated ion channel transcriptome to resolve a role for a Ca(2+) channel in neuromuscular function and regeneration

av Chan, John D., Zhang, Dan, Liu, Xiaolong, Zarowiecki, Magdalena Z., Berriman, Matthew, Marchant, Jonathan S.
I publikationen Biochim Biophys Acta (2016)

Ergot Alkaloids (Re)generate New Leads as Antiparasitics

av Chan, John D., Agbedanu, Prince N., Grab, Thomas, Zamanian, Mostafa, Dosa, Peter I., Day, Timothy A., Marchant, Jonathan S.
I publikationen PLoS Negl Trop Dis (2015)

‘Death and Axes’: Unexpected Ca(2+) Entry Phenologs Predict New Anti-schistosomal Agents

av Chan, John D., Agbedanu, Prince N., Zamanian, Mostafa, Gruba, Sarah M., Haynes, Christy L., Day, Timothy A., Marchant, Jonathan S.
Publicerad 2014

A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors

av Chan, John D., McCorvy, John D., Acharya, Sreemoyee, Johns, Malcolm E., Day, Timothy A., Roth, Bryan L., Marchant, Jonathan S.
I publikationen PLoS Pathog (2016)

The anthelmintic drug praziquantel activates a schistosome transient receptor potential channel

av Park, Sang-Kyu, Gunaratne, Gihan S., Chulkov, Evgeny G., Moehring, Francie, McCusker, Paul, Dosa, Peter I., Chan, John D., Stucky, Cheryl L., Marchant, Jonathan S.
I publikationen J Biol Chem (2019)

The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand

av Chan, John D., Cupit, Pauline M., Gunaratne, Gihan S., McCorvy, John D., Yang, Yang, Stoltz, Kristen, Webb, Thomas R., Dosa, Peter I., Roth, Bryan L., Abagyan, Ruben, Cunningham, Charles, Marchant, Jonathan S.
I publikationen Nat Commun (2017)

Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni

av McCusker, Paul, Mian, Md Yeunus, Li, Guanguan, Olp, Michael D., Tiruveedhula, V. V. N. Phani Babu, Rashid, Farjana, Golani, Lalit Kumar, Verma, Ranjit S., Smith, Brian C., Cook, James M., Chan, John D.
I publikationen PLoS Negl Trop Dis (2019)