Pharmacological and Functional Genetic Assays to Manipulate Regeneration of the Planarian Dugesia japonica

بواسطة Chan, John D., Marchant, Jonathan S.
منشور في 2011

Anti-schistosomal action of the calcium channel agonist FPL-64176

بواسطة McCusker, Paul, Chan, John D.
الحاوية / القاعدة Int J Parasitol Drugs Drug Resist (2019)

Ca(2+) channels and Praziquantel: a view from the free world

بواسطة Chan, John D., Zarowiecki, Magdalena, Marchant, Jonathan S.
منشور في 2012

Kinetic profiling an abundantly expressed planarian serotonergic GPCR identifies bromocriptine as a perdurant antagonist

بواسطة Chan, John D., Grab, Thomas, Marchant, Jonathan S.
الحاوية / القاعدة Int J Parasitol Drugs Drug Resist (2016)

Coalescing beneficial host and deleterious antiparasitic actions as an antischistosomal strategy

بواسطة Chan, John D, Day, Timothy A, Marchant, Jonathan S
الحاوية / القاعدة eLife (2018)

Structure-activity profiling of alkaloid natural product pharmacophores against a Schistosoma serotonin receptor

بواسطة Marchant, Jonathan S., Harding, Wayne W., Chan, John D.
الحاوية / القاعدة Int J Parasitol Drugs Drug Resist (2018)

A Novel Biological Activity of Praziquantel Requiring Voltage-Operated Ca(2+) Channel β Subunits: Subversion of Flatworm Regenerative Polarity

بواسطة Nogi, Taisaku, Zhang, Dan, Chan, John D., Marchant, Jonathan S.
منشور في 2009

Opposing Roles of Voltage-Gated Ca(2+) Channels in Neuronal Control of Regenerative Patterning

بواسطة Zhang, Dan, Chan, John D., Nogi, Taisaku, Marchant, Jonathan S.
منشور في 2011

Characterization of a flatworm inositol (1,4,5) trisphosphate receptor (IP(3)R) reveals a role in reproductive physiology

بواسطة Zhang, Dan, Liu, Xiaolong, Chan, John D., Marchant, Jonathan S.
منشور في 2013

Schistosoma mansoni alter transcription of immunomodulatory gene products following in vivo praziquantel exposure

بواسطة McCusker, Paul, Rohr, Claudia M., Chan, John D.
الحاوية / القاعدة PLoS Negl Trop Dis (2021)

Pharmacological profiling an abundantly expressed schistosome serotonergic GPCR identifies nuciferine as a potent antagonist

بواسطة Chan, John D., Acharya, Sreemoyee, Day, Timothy A., Marchant, Jonathan S.
الحاوية / القاعدة Int J Parasitol Drugs Drug Resist (2016)

Making Heads or Tails: Planarian Stem Cells in the Classroom(†)

بواسطة Srougi, Melissa C., Thomas-Swanik, Jackie, Chan, John D., Marchant, Jonathan S., Carson, Susan
منشور في 2014

Dataset for a Dugesia japonica de novo transcriptome assembly, utilized for defining the voltage-gated like ion channel superfamily

بواسطة Chan, John D., Zhang, Dan, Liu, Xiaolong, Zarowiecki, Magdalena Z., Berriman, Matthew, Marchant, Jonathan S.
الحاوية / القاعدة Data Brief (2016)

Utilizing the planarian voltage-gated ion channel transcriptome to resolve a role for a Ca(2+) channel in neuromuscular function and regeneration

بواسطة Chan, John D., Zhang, Dan, Liu, Xiaolong, Zarowiecki, Magdalena Z., Berriman, Matthew, Marchant, Jonathan S.
الحاوية / القاعدة Biochim Biophys Acta (2016)

Ergot Alkaloids (Re)generate New Leads as Antiparasitics

بواسطة Chan, John D., Agbedanu, Prince N., Grab, Thomas, Zamanian, Mostafa, Dosa, Peter I., Day, Timothy A., Marchant, Jonathan S.
الحاوية / القاعدة PLoS Negl Trop Dis (2015)

‘Death and Axes’: Unexpected Ca(2+) Entry Phenologs Predict New Anti-schistosomal Agents

بواسطة Chan, John D., Agbedanu, Prince N., Zamanian, Mostafa, Gruba, Sarah M., Haynes, Christy L., Day, Timothy A., Marchant, Jonathan S.
منشور في 2014

A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors

بواسطة Chan, John D., McCorvy, John D., Acharya, Sreemoyee, Johns, Malcolm E., Day, Timothy A., Roth, Bryan L., Marchant, Jonathan S.
الحاوية / القاعدة PLoS Pathog (2016)

The anthelmintic drug praziquantel activates a schistosome transient receptor potential channel

بواسطة Park, Sang-Kyu, Gunaratne, Gihan S., Chulkov, Evgeny G., Moehring, Francie, McCusker, Paul, Dosa, Peter I., Chan, John D., Stucky, Cheryl L., Marchant, Jonathan S.
الحاوية / القاعدة J Biol Chem (2019)

The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand

بواسطة Chan, John D., Cupit, Pauline M., Gunaratne, Gihan S., McCorvy, John D., Yang, Yang, Stoltz, Kristen, Webb, Thomas R., Dosa, Peter I., Roth, Bryan L., Abagyan, Ruben, Cunningham, Charles, Marchant, Jonathan S.
الحاوية / القاعدة Nat Commun (2017)

Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni

بواسطة McCusker, Paul, Mian, Md Yeunus, Li, Guanguan, Olp, Michael D., Tiruveedhula, V. V. N. Phani Babu, Rashid, Farjana, Golani, Lalit Kumar, Verma, Ranjit S., Smith, Brian C., Cook, James M., Chan, John D.
الحاوية / القاعدة PLoS Negl Trop Dis (2019)