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Schistosoma mansoni alter transcription of immunomodulatory gene products following in vivo praziquantel exposure

Control of the neglected tropical disease schistosomiasis relies almost entirely on praziquantel (PZQ) monotherapy. How PZQ clears parasite infections remains poorly understood. Many studies have examined the effects of PZQ on worms cultured in vitro, observing outcomes such as muscle contraction. H...

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Bibliografiske detaljer
Udgivet i:PLoS Negl Trop Dis
Main Authors: McCusker, Paul, Rohr, Claudia M., Chan, John D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959349/
https://ncbi.nlm.nih.gov/pubmed/33657133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0009200
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