‘Death and Axes’: Unexpected Ca(2+) Entry Phenologs Predict New Anti-schistosomal Agents

Schistosomiasis is a parasitic flatworm disease that infects 200 million people worldwide. The drug praziquantel (PZQ) is the mainstay therapy but the target of this drug remains ambiguous. While PZQ paralyses and kills parasitic schistosomes, in free-living planarians PZQ caused an unusual axis dup...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chan, John D., Agbedanu, Prince N., Zamanian, Mostafa, Gruba, Sarah M., Haynes, Christy L., Day, Timothy A., Marchant, Jonathan S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930560/
https://ncbi.nlm.nih.gov/pubmed/24586156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003942
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