‘Death and Axes’: Unexpected Ca(2+) Entry Phenologs Predict New Anti-schistosomal Agents

Schistosomiasis is a parasitic flatworm disease that infects 200 million people worldwide. The drug praziquantel (PZQ) is the mainstay therapy but the target of this drug remains ambiguous. While PZQ paralyses and kills parasitic schistosomes, in free-living planarians PZQ caused an unusual axis dup...

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Detalhes bibliográficos
Main Authors: Chan, John D., Agbedanu, Prince N., Zamanian, Mostafa, Gruba, Sarah M., Haynes, Christy L., Day, Timothy A., Marchant, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930560/
https://ncbi.nlm.nih.gov/pubmed/24586156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003942
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