The aged niche disrupts muscle stem cell quiescence

le Chakkalakal, Joe V., Jones, Kieran M., Basson, M. Albert, Brack, Andrew S.
Foilsithe 2012

Smad4 restricts differentiation to promote expansion of satellite cell derived progenitors during skeletal muscle regeneration

le Paris, Nicole D, Soroka, Andrew, Klose, Alanna, Liu, Wenxuan, Chakkalakal, Joe V
Foilsithe in eLife (2016)

Modulation of utrophin A mRNA stability in fast versus slow muscles via an AU-rich element and calcineurin signaling

le Chakkalakal, Joe V., Miura, Pedro, Bélanger, Guy, Michel, Robin N., Jasmin, Bernard J.
Foilsithe 2008

MOUSE TRANSGENIC LINES THAT SELECTIVELY LABEL TYPE I, TYPE IIA AND TYPES IIX+B SKELETAL MUSCLE FIBERS

le Chakkalakal, Joe V., Kuang, Shihuan, Buffelli, Mario, Lichtman, Jeff W., Sanes, Joshua R.
Foilsithe 2012

Inducible depletion of adult skeletal muscle stem cells impairs the regeneration of neuromuscular junctions

le Liu, Wenxuan, Wei-LaPierre, Lan, Klose, Alanna, Dirksen, Robert T, Chakkalakal, Joe V
Foilsithe in eLife (2015)

Retrograde influence of muscle fibers on their innervation revealed by a novel marker for slow motoneurons

le Chakkalakal, Joe V., Nishimune, Hiroshi, Ruas, Jorge L., Spiegelman, Bruce M., Sanes, Joshua R.
Foilsithe 2010

Early forming label-retaining muscle stem cells require p27(kip1) for maintenance of the primitive state

le Chakkalakal, Joe V., Christensen, Josef, Xiang, Wanyi, Tierney, Mathew T., Boscolo, Francesca S., Sacco, Alessandra, Brack, Andrew S.
Foilsithe 2014

TGFβ Superfamily Members Mediate Androgen Deprivation Therapy-Induced Obese Frailty in Male Mice

le Pan, Chunliu, Singh, Shalini, Sahasrabudhe, Deepak M., Chakkalakal, Joe V., Krolewski, John J., Nastiuk, Kent L.
Foilsithe in Endocrinology (2016)

Inhibition of inflammatory CCR2 signaling promotes aged muscle regeneration and strength recovery after injury

le Blanc, Roméo S., Kallenbach, Jacob G., Bachman, John F., Mitchell, Amanda, Paris, Nicole D., Chakkalakal, Joe V.
Foilsithe in Nat Commun (2020)

Addressing the Symptoms or Fixing the Problem? Developing Countermeasures against Normal Tissue Radiation Injury

le Williams, Jacqueline P., Calvi, Laura, Chakkalakal, Joe V., Finkelstein, Jacob N., O’Banion, M. Kerry, Puzas, Edward
Foilsithe in Radiat Res (2016)

Castration induces satellite cell activation that contributes to skeletal muscle maintenance

le Klose, Alanna, Liu, Wenxuan, Paris, Nicole D., Forman, Sophie, Krolewski, John J., Nastiuk, Kent L., Chakkalakal, Joe V.
Foilsithe in JCSM Rapid Commun (2018)

Prepubertal skeletal muscle growth requires Pax7-expressing satellite cell-derived myonuclear contribution

le Bachman, John F., Klose, Alanna, Liu, Wenxuan, Paris, Nicole D., Blanc, Roméo S., Schmalz, Melissa, Knapp, Emma, Chakkalakal, Joe V.
Foilsithe in Development (2018)

Chemoradiation impairs myofiber hypertrophic growth in a pediatric tumor model

le Paris, Nicole D., Kallenbach, Jacob G., Bachman, John F., Blanc, Roméo S., Johnston, Carl J., Hernady, Eric, Williams, Jacqueline P., Chakkalakal, Joe V.
Foilsithe in Sci Rep (2020)

Radiation-Induced Damage to Prepubertal Pax7+ Skeletal Muscle Stem Cells Drives Lifelong Deficits in Myofiber Size and Nuclear Number

le Bachman, John F., Blanc, Roméo S., Paris, Nicole D., Kallenbach, Jacob G., Johnston, Carl J., Hernady, Eric, Williams, Jacqueline P., Chakkalakal, Joe V.
Foilsithe in iScience (2020)

Prostate tumor–derived GDF11 accelerates androgen deprivation therapy–induced sarcopenia

le Pan, Chunliu, Jaiswal Agrawal, Neha, Zulia, Yanni, Singh, Shalini, Sha, Kai, Mohler, James L., Eng, Kevin H., Chakkalakal, Joe V., Krolewski, John J., Nastiuk, Kent L.
Foilsithe in JCI Insight (2020)

Loss of adult skeletal muscle stem cells drives age-related neuromuscular junction degeneration

le Liu, Wenxuan, Klose, Alanna, Forman, Sophie, Paris, Nicole D, Wei-LaPierre, Lan, Cortés-Lopéz, Mariela, Tan, Aidi, Flaherty, Morgan, Miura, Pedro, Dirksen, Robert T, Chakkalakal, Joe V
Foilsithe in eLife (2017)

Increased myocellular lipid and IGFBP‐3 expression in a pre‐clinical model of pancreatic cancer‐related skeletal muscle wasting

le Cole, Calvin L., Bachman, John F., Ye, Jian, Murphy, Joseph, Gerber, Scott A., Beck, Christopher A., Boyce, Brendan F., Muthukrishnan, Gowrishankar, Chakkalakal, Joe V., Schwarz, Edward M., Linehan, David
Foilsithe in J Cachexia Sarcopenia Muscle (2021)

Expression of utrophin A mRNA correlates with the oxidative capacity of skeletal muscle fiber types and is regulated by calcineurin/NFAT signaling

le Chakkalakal, Joe V., Stocksley, Mark A., Harrison, Mary-Ann, Angus, Lindsay M., Deschênes-Furry, Julie, St-Pierre, Simon, Megeney, Lynn A., Chin, Eva R., Michel, Robin N., Jasmin, Bernard J.
Foilsithe 2003

Research Priorities in Cancer Cachexia: The University of Rochester Cancer Center NCI Community Oncology Research Program (NCORP) Research Base Symposium on Cancer Cachexia and Sar...

le Dunne, Richard F., Mustian, Karen M., Garcia, Jose M., Dale, William, Hayward, Reid, Roussel, Breton, Buschmann, Mary M., Caan, Bette J., Cole, Calvin L., Fleming, Fergal J., Chakkalakal, Joe V., Linehan, David C., Hezel, Aram F., Mohile, Supriya G.
Foilsithe in Curr Opin Support Palliat Care (2017)

Selective sexual dimorphism in musculoskeletal-cardiopulmonary pathologies and mortality in the TNF-transgenic mouse model of rheumatoid arthritis

le Bell, Richard D, Wu, Emily K, Rudmann, Christopher A, Forney, Megan, Kaiser, Claire R W, Wood, Ronald W, Chakkalakal, Joe V, Paris, Nicole D, Klose, Alanna, Xiao, Guang-Qian, Rangel-Moreno, Javier, Garcia-Hernandez, Maria L, Ritchlin, Christopher T, Schwarz, Edward M, Rahimi, Homaira
Foilsithe in Arthritis Rheumatol (2019)