Loss of adult skeletal muscle stem cells drives age-related neuromuscular junction degeneration

Neuromuscular junction degeneration is a prominent aspect of sarcopenia, the age-associated loss of skeletal muscle integrity. Previously, we showed that muscle stem cells activate and contribute to mouse neuromuscular junction regeneration in response to denervation (Liu et al., 2015). Here, we exa...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Liu, Wenxuan, Klose, Alanna, Forman, Sophie, Paris, Nicole D, Wei-LaPierre, Lan, Cortés-Lopéz, Mariela, Tan, Aidi, Flaherty, Morgan, Miura, Pedro, Dirksen, Robert T, Chakkalakal, Joe V
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Developmental Biology and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462534/
https://ncbi.nlm.nih.gov/pubmed/28583253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26464
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