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Chemoradiation impairs myofiber hypertrophic growth in a pediatric tumor model

Pediatric cancer treatment often involves chemotherapy and radiation, where off-target effects can include skeletal muscle decline. The effect of such treatments on juvenile skeletal muscle growth has yet to be investigated. We employed a small animal irradiator to administer fractionated hindlimb i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Paris, Nicole D., Kallenbach, Jacob G., Bachman, John F., Blanc, Roméo S., Johnston, Carl J., Hernady, Eric, Williams, Jacqueline P., Chakkalakal, Joe V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659015/
https://ncbi.nlm.nih.gov/pubmed/33177579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75913-w
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