Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases

Por Chen, Li-Mei, Chai, Karl X.
Publicado no Oncotarget (2017)

Loss of prostasin (PRSS8) in human bladder transitional cell carcinoma cell lines is associated with epithelial-mesenchymal transition (EMT)

Por Chen, Li-Mei, Verity, Nicole J, Chai, Karl X
Publicado em 2009

The Epidermal Growth Factor Receptor (EGFR) Is Proteolytically Modified by the Matriptase-Prostasin Serine Protease Cascade in Cultured Epithelial Cells

Por Chen, Mengqian, Chen, Li-Mei, Lin, Chen-Yong, Chai, Karl X.
Publicado em 2007

Ibuprofen regulates the expression and function of membrane-associated serine proteases prostasin and matriptase

Por Chai, Andreas C., Robinson, Andrew L., Chai, Karl X., Chen, Li-Mei
Publicado no BMC Cancer (2015)

Prostasin induces protease-dependent and independent molecular changes in the human prostate carcinoma cell line PC-3

Por Chen, Mengqian, Fu, Ya-Yuan, Lin, Chen-Yong, Chen, Li-Mei, Chai, Karl X.
Publicado em 2007

Long-Term Exposure to Cigarette Smoke Extract Induces Hypomethylation at the RUNX3 and IGF2-H19 Loci in Immortalized Human Urothelial Cells

Por Chen, Li-Mei, Nergard, Jennifer C., Ni, Liqiang, Rosser, Charles J., Chai, Karl X.
Publicado em 2013

Proteasome Inhibition Augments Cigarette Smoke-Induced GM-CSF Expression in Trophoblast Cells via the Epidermal Growth Factor Receptor

Por Fu, Ya-Yuan, Nergard, Jennifer C., Barnette, Nicole K., Wang, Yan-Ling, Chai, Karl X., Chen, Li-Mei
Publicado em 2012

The HIV-1 gp41 ectodomain is cleaved by matriptase to produce a chemotactic peptide that acts through FPR2

Por Wood, Matthew P, Cole, Amy L, Eade, Colleen R, Chen, Li-Mei, Chai, Karl X, Cole, Alexander M
Publicado em 2014

Expression of Prostasin and Protease Nexin-1 in Rhesus Monkey (Macaca mulatta) Endometrium and Placenta During Early Pregnancy

Por Lin, Hai-Yan, Zhang, Heng, Yang, Qing, Wang, Hong-Xing, Wang, Hong-Mei, Chai, Karl X., Chen, Li-Mei, Zhu, Cheng
Publicado em 2006

Regulation of prostasin by aldosterone in the kidney

Por Narikiyo, Takefumi, Kitamura, Kenichiro, Adachi, Masataka, Miyoshi, Taku, Iwashita, Kozo, Shiraishi, Naoki, Nonoguchi, Hiroshi, Chen, Li-Mei, Chai, Karl X., Chao, Julie, Tomita, Kimio
Publicado em 2002

TIMP-1 via TWIST1 Induces EMT Phenotypes in Human Breast Epithelial Cells

Por D’Angelo, Rosemarie Chirco, Liu, Xu-Wen, Najy, Abdo J., Jung, Young Suk, Won, Joshua, Chai, Karl X., Fridman, Rafael, Kim, Hyeong-Reh Choi
Publicado em 2014

HIV-1 Enhancing Effect of Prostatic Acid Phosphatase Peptides Is Reduced in Human Seminal Plasma

Por Martellini, Julie A., Cole, Amy L., Svoboda, Pavel, Stuchlik, Olga, Chen, Li-Mei, Chai, Karl X., Gangrade, Bhushan K., Sørensen, Ole E., Pohl, Jan, Cole, Alexander M.
Publicado em 2011

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade

Por Xu, Zhenghong, Chen, Ya-Wen, Battu, Aruna, Wilder, Paul, Weber, David, Yu, Wenbo, MacKerell, Alexander D., Chen, Li-Mei, Chai, Karl X., Johnson, Michael D., Lin, Chen-Yong
Publicado em 2011

Intravesical ALT-803 and BCG Treatment Reduces Tumor Burden in a Carcinogen Induced Bladder Cancer Rat Model; a Role for Cytokine Production and NK Cell Expansion

Por Gomes-Giacoia, Evan, Miyake, Makito, Goodison, Steve, Sriharan, Aravindhan, Zhang, Ge, You, Lijing, Egan, Jack O., Rhode, Peter R., Parker, Alexander S., Chai, Karl X., Wong, Hing C., Rosser, Charles J.
Publicado em 2014

Regulation of the Matriptase-Prostasin Cell Surface Proteolytic Cascade by Hepatocyte Growth Factor Activator Inhibitor-1 during Epidermal Differentiation

Por Chen(陳, Ya-Wen, 亞雯), Wang(王, Jehng-Kang, 正康), Chou(周, Feng-Pai, 封百), Chen(陳, Chiu-Yuan, 秋媛), Rorke, Ellen A., Chen, Li-Mei, Chai, Karl X., Eckert, Richard L., Johnson, Michael D., Lin(林, Chen-Yong, 陳鏞)
Publicado em 2010

External Validation of a Multiplex Urinary Protein Panel for the Detection of Bladder Cancer in a Multicenter Cohort

Por Chen, Li-Mei, Chang, Myron, Dai, Yunfeng, Chai, Karl X., Dyrskjøt, Lars, Sanchez-Carbayo, Marta, Szarvas, Tibor, Zwarthoff, Ellen C., Lokeshwar, Vinata, Jeronimo, Carmen, Parker, Alexander S., Ross, Shanti, Borre, Michael, Ørntoft, Torben F., Jaeger, Tobias, Beukers, Willemien, Lopez, Luis E., Henrique, Rui, Young, Paul R., Urquidi, Virginia, Goodison, Steve, Rosser, Charles J.
Publicado em 2014