Proteasome Inhibition Augments Cigarette Smoke-Induced GM-CSF Expression in Trophoblast Cells via the Epidermal Growth Factor Receptor

Maternal cigarette smoking has adverse effects on pregnancy outcomes. The granulocyte-macrophage colony-stimulating factor (GM-CSF) is an essential cytokine for a normal pregnancy. We investigated the impact of cigarette smoke extract (CSE) on GM-CSF expression in human cytotrophoblast cells and sug...

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Detalhes bibliográficos
Main Authors: Fu, Ya-Yuan, Nergard, Jennifer C., Barnette, Nicole K., Wang, Yan-Ling, Chai, Karl X., Chen, Li-Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422336/
https://ncbi.nlm.nih.gov/pubmed/22912784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043042
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