A Fruitful Endeavor: Modeling ALS in the Fruit Fly

per Casci, Ian, Pandey, Udai Bhan
Publicat a Brain Res (2014)

Identifying dominant modifiers of mutant FUS toxicity in vivo

per Daigle, J Gavin, Lanson, Nicholas A, Casci, Ian, Monaghan, John, Nichols, Charles, Kryndushkin, Dimitri, Shewmaker, Frank, Pandey, Udai
Publicat 2013

Protein Arginine Methyltransferase 1 and 8 Interact with FUS to Modify Its Sub-Cellular Distribution and Toxicity In Vitro and In Vivo

per Scaramuzzino, Chiara, Monaghan, John, Milioto, Carmelo, Lanson, Nicholas A., Maltare, Astha, Aggarwal, Tanya, Casci, Ian, Fackelmayer, Frank O., Pennuto, Maria, Pandey, Udai Bhan
Publicat 2013

RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations

per Daigle, J. Gavin, Lanson, Nicholas A., Smith, Rebecca B., Casci, Ian, Maltare, Astha, Monaghan, John, Nichols, Charles D., Kryndushkin, Dmitri, Shewmaker, Frank, Pandey, Udai Bhan
Publicat 2013

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity

per Daigle, J Gavin, Krishnamurthy, Karthik, Ramesh, Nandini, Casci, Ian, Monaghan, John, McAvoy, Kevin, Godfrey, Earl W, Daniel, Dianne C., Johnson, Edward M., Monahan, Zach, Shewmaker, Frank, Pasinelli, Piera, Pandey, Udai Bhan
Publicat a Acta Neuropathol (2016)

Protein Arginine Methyltransferase 6 Enhances Polyglutamine-Expanded Androgen Receptor Function and Toxicity in Spinal and Bulbar Muscular Atrophy

per Scaramuzzino, Chiara, Casci, Ian, Parodi, Sara, Lievens, Patricia M.J., Polanco, Maria J., Milioto, Carmelo, Chivet, Mathilde, Monaghan, John, Mishra, Ashutosh, Badders, Nisha, Aggarwal, Tanya, Grunseich, Christopher, Sambataro, Fabio, Basso, Manuela, Fackelmayer, Frank O., Taylor, J. Paul, Pandey, Udai Bhan, Pennuto, Maria
Publicat a Neuron (2015)

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy

per Marrone, Lara, Poser, Ina, Casci, Ian, Japtok, Julia, Reinhardt, Peter, Janosch, Antje, Andree, Cordula, Lee, Hyun O., Moebius, Claudia, Koerner, Ellen, Reinhardt, Lydia, Cicardi, Maria Elena, Hackmann, Karl, Klink, Barbara, Poletti, Angelo, Alberti, Simon, Bickle, Marc, Hermann, Andreas, Pandey, Udai Bhan, Hyman, Anthony A., Sterneckert, Jared L.
Publicat a Stem Cell Reports (2018)

Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization

per Casci, Ian, Krishnamurthy, Karthik, Kour, Sukhleen, Tripathy, Vadreenath, Ramesh, Nandini, Anderson, Eric N., Marrone, Lara, Grant, Rogan A., Oliver, Stacie, Gochenaur, Lauren, Patel, Krishani, Sterneckert, Jared, Gleixner, Amanda M., Donnelly, Christopher J., Ruepp, Marc-David, Sini, Antonella M., Zuccaro, Emanuela, Pennuto, Maria, Pasinelli, Piera, Pandey, Udai Bhan
Publicat a Nat Commun (2019)