Phospholipase Cζ binding to PtdIns(4,5)P(2) requires the XY-linker region

Por Nomikos, Michail, Elgmati, Khalil, Theodoridou, Maria, Calver, Brian L., Nounesis, George, Swann, Karl, Lai, F. Anthony
Publicado em 2011

Inflammation and frailty measures in older people

Por Hubbard, Ruth E, O’Mahony, M Sinead, Savva, George M, Calver, Brian L, Woodhouse, Ken W
Publicado no J Cell Mol Med (2009)

Male infertility-linked point mutation disrupts the Ca(2+) oscillation-inducing and PIP(2) hydrolysis activity of sperm PLCζ

Por Nomikos, Michail, Elgmati, Khalil, Theodoridou, Maria, Calver, Brian L., Cumbes, Bevan, Nounesis, Georg, Swann, Karl, Lai, F. Anthony
Publicado em 2011

Human PLCζ exhibits superior fertilization potency over mouse PLCζ in triggering the Ca(2+) oscillations required for mammalian oocyte activation

Por Nomikos, Michail, Theodoridou, Maria, Elgmati, Khalil, Parthimos, Dimitris, Calver, Brian L., Buntwal, Luke, Nounesis, George, Swann, Karl, Lai, F. Anthony
Publicado em 2014

Chimeras of sperm PLCζ reveal disparate protein domain functions in the generation of intracellular Ca(2+) oscillations in mammalian eggs at fertilization

Por Theodoridou, Maria, Nomikos, Michail, Parthimos, Dimitris, Gonzalez-Garcia, J. Raul, Elgmati, Khalil, Calver, Brian L., Sideratou, Zili, Nounesis, George, Swann, Karl, Lai, F. Anthony
Publicado em 2013

Essential Role of the EF-hand Domain in Targeting Sperm Phospholipase Cζ to Membrane Phosphatidylinositol 4,5-Bisphosphate (PIP(2))

Por Nomikos, Michail, Sanders, Jessica R., Parthimos, Dimitris, Buntwal, Luke, Calver, Brian L., Stamatiadis, Panagiotis, Smith, Adrian, Clue, Matthew, Sideratou, Zili, Swann, Karl, Lai, F. Anthony
Publicado no J Biol Chem (2015)