Protein Engineering Towards Natural Product Synthesis and Diversification

Por Zabala, Angelica O., Cacho, Ralph A., Tang, Yi
Publicado em 2011

Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi

Por Cacho, Ralph A., Tang, Yi, Chooi, Yit-Heng
Publicado no Front Microbiol (2015)

Complexity generation in fungal polyketide biosynthesis: a spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin

Por Cacho, Ralph A., Chooi, Yit-Heng, Zhou, Hui, Tang, Yi
Publicado em 2013

Identification and Characterization of the Echinocandin B Biosynthetic Gene Cluster from Emericella rugulosa NRRL 11440

Por Cacho, Ralph A., Jiang, Wei, Chooi, Yit-Heng, Walsh, Christopher T., Tang, Yi
Publicado em 2012

EcdGHK are Three Tailoring Iron Oxygenases for Amino Acid Building Blocks of the Echinocandin Scaffold

Por Jiang, Wei, Cacho, Ralph A, Chiou, Grace, Garg, Neil K, Tang, Yi, Walsh, Christopher T
Publicado em 2013

A Cytochrome P450 Serves as an Unexpected Terpene Cyclase during Fungal Meroterpenoid Biosynthesis

Por Chooi, Yit-Heng, Hong, Young J., Cacho, Ralph A., Tantillo, Dean J., Tang, Yi
Publicado em 2013

Understanding Programming of Fungal Iterative Polyketide Synthases: the Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the Lovastatin Megasynthase

Por Cacho, Ralph A., Thuss, Justin, Xu, Wei, Sanichar, Randy, Gao, Zhizeng, Nguyen, Allison, Vederas, John C., Tang, Yi
Publicado no J Am Chem Soc (2015)

Discovery of Cryptic Polyketide Metabolites from Dermatophytes using Heterologous Expression in Aspergillus nidulans

Por Yin, Wen-Bing, Chooi, Yit Heng, Smith, Adam R., Cacho, Ralph A., Hu, Youcai, White, Theodore C., Tang, Yi
Publicado em 2013

Structural basis of nonribosomal peptide macrocyclization in fungi

Por Zhang, Jinru, Liu, Nicholas, Cacho, Ralph A., Gong, Zhou, Liu, Zhu, Qin, Wenming, Tang, Chun, Tang, Yi, Zhou, Jiahai
Publicado no Nat Chem Biol (2016)

Discovery of Unclustered Fungal Indole Diterpene Biosynthetic Pathways through Combinatorial Pathway Reassembly in Engineered Yeast

Por Tang, Mancheng, Lin, Hsiao-Ching, Li, Dehai, Zou, Yi, Li, Jian, Xu, Wei, Cacho, Ralph A., Hillenmeyer, Maureen E., Garg, Neil K., Tang, Yi
Publicado no J Am Chem Soc (2015)