Protein Engineering Towards Natural Product Synthesis and Diversification

Autor Zabala, Angelica O., Cacho, Ralph A., Tang, Yi
Vydáno 2011

Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi

Autor Cacho, Ralph A., Tang, Yi, Chooi, Yit-Heng
Vydáno v Front Microbiol (2015)

Complexity generation in fungal polyketide biosynthesis: a spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin

Autor Cacho, Ralph A., Chooi, Yit-Heng, Zhou, Hui, Tang, Yi
Vydáno 2013

Mechanism of the P450-Catalyzed Oxidative Cyclization in the Biosynthesis of Griseofulvin

Autor Grandner, Jessica M., Cacho, Ralph A., Tang, Yi, Houk, K. N.
Vydáno v ACS Catal (2016)

Identification and Characterization of the Echinocandin B Biosynthetic Gene Cluster from Emericella rugulosa NRRL 11440

Autor Cacho, Ralph A., Jiang, Wei, Chooi, Yit-Heng, Walsh, Christopher T., Tang, Yi
Vydáno 2012

EcdGHK are Three Tailoring Iron Oxygenases for Amino Acid Building Blocks of the Echinocandin Scaffold

Autor Jiang, Wei, Cacho, Ralph A, Chiou, Grace, Garg, Neil K, Tang, Yi, Walsh, Christopher T
Vydáno 2013

A Cytochrome P450 Serves as an Unexpected Terpene Cyclase during Fungal Meroterpenoid Biosynthesis

Autor Chooi, Yit-Heng, Hong, Young J., Cacho, Ralph A., Tantillo, Dean J., Tang, Yi
Vydáno 2013

Understanding Programming of Fungal Iterative Polyketide Synthases: the Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the Lovastatin Megasynthase

Autor Cacho, Ralph A., Thuss, Justin, Xu, Wei, Sanichar, Randy, Gao, Zhizeng, Nguyen, Allison, Vederas, John C., Tang, Yi
Vydáno v J Am Chem Soc (2015)

Discovery of Cryptic Polyketide Metabolites from Dermatophytes using Heterologous Expression in Aspergillus nidulans

Autor Yin, Wen-Bing, Chooi, Yit Heng, Smith, Adam R., Cacho, Ralph A., Hu, Youcai, White, Theodore C., Tang, Yi
Vydáno 2013

Structural basis of nonribosomal peptide macrocyclization in fungi

Autor Zhang, Jinru, Liu, Nicholas, Cacho, Ralph A., Gong, Zhou, Liu, Zhu, Qin, Wenming, Tang, Chun, Tang, Yi, Zhou, Jiahai
Vydáno v Nat Chem Biol (2016)

Discovery of Unclustered Fungal Indole Diterpene Biosynthetic Pathways through Combinatorial Pathway Reassembly in Engineered Yeast

Autor Tang, Mancheng, Lin, Hsiao-Ching, Li, Dehai, Zou, Yi, Li, Jian, Xu, Wei, Cacho, Ralph A., Hillenmeyer, Maureen E., Garg, Neil K., Tang, Yi
Vydáno v J Am Chem Soc (2015)