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Mechanism of the P450-Catalyzed Oxidative Cyclization in the Biosynthesis of Griseofulvin
Griseofulvin is an anti-fungal agent which has recently been determined to have potential anti-viral and anti-cancer applications. The role of specific enzymes involved in the biosynthesis of this natural product has previously been determined, but the mechanism by which a p450, GsfF, catalyzes the...
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| Publicado no: | ACS Catal |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5425163/ https://ncbi.nlm.nih.gov/pubmed/28503354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.6b01068 |
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