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Mechanism of the P450-Catalyzed Oxidative Cyclization in the Biosynthesis of Griseofulvin

Griseofulvin is an anti-fungal agent which has recently been determined to have potential anti-viral and anti-cancer applications. The role of specific enzymes involved in the biosynthesis of this natural product has previously been determined, but the mechanism by which a p450, GsfF, catalyzes the...

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Xehetasun bibliografikoak
Argitaratua izan da:ACS Catal
Egile Nagusiak: Grandner, Jessica M., Cacho, Ralph A., Tang, Yi, Houk, K. N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425163/
https://ncbi.nlm.nih.gov/pubmed/28503354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.6b01068
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