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Discovery of Cryptic Polyketide Metabolites from Dermatophytes using Heterologous Expression in Aspergillus nidulans

Dermatophytes belonging to the Trichophyton and Arthroderma genera cause skin infections in humans and animals. From genome sequencing data, we mined a conserved gene cluster among dermatophytes that are homologous to one that produces an immunosuppressive polyketide in Aspergillus fumigatus. Using...

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Main Authors: Yin, Wen-Bing, Chooi, Yit Heng, Smith, Adam R., Cacho, Ralph A., Hu, Youcai, White, Theodore C., Tang, Yi
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795930/
https://ncbi.nlm.nih.gov/pubmed/23758576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/sb400048b
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