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Discovery of Cryptic Polyketide Metabolites from Dermatophytes using Heterologous Expression in Aspergillus nidulans

Dermatophytes belonging to the Trichophyton and Arthroderma genera cause skin infections in humans and animals. From genome sequencing data, we mined a conserved gene cluster among dermatophytes that are homologous to one that produces an immunosuppressive polyketide in Aspergillus fumigatus. Using...

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Détails bibliographiques
Auteurs principaux: Yin, Wen-Bing, Chooi, Yit Heng, Smith, Adam R., Cacho, Ralph A., Hu, Youcai, White, Theodore C., Tang, Yi
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795930/
https://ncbi.nlm.nih.gov/pubmed/23758576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/sb400048b
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