Performance and Robustness of the Monte Carlo Importance Sampling Algorithm Using Parallelized S-ADAPT for Basic and Complex Mechanistic Models

por Bulitta, Jurgen B., Landersdorfer, Cornelia B.
Publicado em 2011

Impact of Two-Component Regulatory Systems PhoP-PhoQ and PmrA-PmrB on Colistin Pharmacodynamics in Pseudomonas aeruginosa

por Ly, Neang S., Yang, Jenny, Bulitta, Jurgen B., Tsuji, Brian T.
Publicado em 2012

Distinguishing Antimicrobial Models with Different Resistance Mechanisms via Population Pharmacodynamic Modeling

por Jacobs, Matthieu, Grégoire, Nicolas, Couet, William, Bulitta, Jurgen B.
Publicado no PLoS Comput Biol (2016)

Development of a New Pre- and Post-Processing Tool (SADAPT-TRAN) for Nonlinear Mixed-Effects Modeling in S-ADAPT

por Bulitta, Jurgen Bernd, Bingölbali, Ayhan, Shin, Beom Soo, Landersdorfer, Cornelia Barbara
Publicado em 2011

Development and validation of a liquid chromatography - mass spectrometry assay for polymyxin B in bacterial growth media

por Cheah, Soon-Ee, Bulitta, Jurgen B., Li, Jian, Nation, Roger L.
Publicado em 2014

Novel Rate-Area-Shape Modeling Approach To Quantify Bacterial Killing and Regrowth for In Vitro Static Time-Kill Studies

por Cheah, Soon-Ee, Li, Jian, Nation, Roger L., Bulitta, Jürgen B.
Publicado no Antimicrob Agents Chemother (2014)

Optimization of Synergistic Combination Regimens against Carbapenem- and Aminoglycoside-Resistant Clinical Pseudomonas aeruginosa Isolates via Mechanism-Based Pharmacokinetic/Pharm...

por Yadav, Rajbharan, Bulitta, Jürgen B., Nation, Roger L., Landersdorfer, Cornelia B.
Publicado no Antimicrob Agents Chemother (2016)

Quantifying Subpopulation Synergy for Antibiotic Combinations via Mechanism-Based Modeling and a Sequential Dosing Design

por Landersdorfer, Cornelia B., Ly, Neang S., Xu, Hongmei, Tsuji, Brian T., Bulitta, Jürgen B.
Publicado em 2013

Evaluation of Pharmacokinetic/Pharmacodynamic Model-Based Optimized Combination Regimens against Multidrug-Resistant Pseudomonas aeruginosa in a Murine Thigh Infection Model by Usi...

por Yadav, Rajbharan, Bulitta, Jürgen B., Wang, Jiping, Nation, Roger L., Landersdorfer, Cornelia B.
Publicado no Antimicrob Agents Chemother (2017)

Novel Approach To Optimize Synergistic Carbapenem-Aminoglycoside Combinations against Carbapenem-Resistant Acinetobacter baumannii

por Yadav, Rajbharan, Landersdorfer, Cornelia B., Nation, Roger L., Boyce, John D., Bulitta, Jürgen B.
Publicado no Antimicrob Agents Chemother (2015)

Evaluation of Tobramycin and Ciprofloxacin as a Synergistic Combination Against Hypermutable Pseudomonas Aeruginosa Strains via Mechanism-Based Modelling

por Rees, Vanessa E., Bulitta, Jürgen B., Oliver, Antonio, Nation, Roger L., Landersdorfer, Cornelia B.
Publicado no Pharmaceutics (2019)

Development and Qualification of a Pharmacodynamic Model for the Pronounced Inoculum Effect of Ceftazidime against Pseudomonas aeruginosa

por Bulitta, Jürgen B., Ly, Neang S., Yang, Jenny C., Forrest, Alan, Jusko, William J., Tsuji, Brian T.
Publicado em 2009

Modeling the Autoinhibition of Clarithromycin Metabolism during Repeated Oral Administration

por Abduljalil, Khaled, Kinzig, Martina, Bulitta, Jürgen, Horkovics-Kovats, Stefan, Sörgel, Fritz, Rodamer, Michael, Fuhr, Uwe
Publicado em 2009

Pharmacokinetic/Pharmacodynamic Investigation of Colistin against Pseudomonas aeruginosa Using an In Vitro Model

por Bergen, Phillip J., Bulitta, Jurgen B., Forrest, Alan, Tsuji, Brian T., Li, Jian, Nation, Roger L.
Publicado em 2010

Nonlinear pharmacokinetics of piperacillin in healthy volunteers – implications for optimal dosage regimens

por Bulitta, Jürgen B, Kinzig, Martina, Jakob, Verena, Holzgrabe, Ulrike, Sörgel, Fritz, Holford, Nicholas H G
Publicado em 2010

Colistin and Polymyxin B Dosage Regimens against Acinetobacter baumannii: Differences in Activity and the Emergence of Resistance

por Cheah, Soon-Ee, Li, Jian, Tsuji, Brian T., Forrest, Alan, Bulitta, Jürgen B., Nation, Roger L.
Publicado no Antimicrob Agents Chemother (2016)

Inhibition of flucloxacillin tubular renal secretion by piperacillin

por Landersdorfer, Cornelia B, Kirkpatrick, Carl M J, Kinzig, Martina, Bulitta, Jürgen B, Holzgrabe, Ulrike, Sörgel, Fritz
Publicado em 2008

Mechanism-Based Model of Parasite Growth and Dihydroartemisinin Pharmacodynamics in Murine Malaria

por Patel, Kashyap, Batty, Kevin T., Moore, Brioni R., Gibbons, Peter L., Bulitta, Jürgen B., Kirkpatrick, Carl M.
Publicado em 2013

Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin

por Bulman, Zackery P., Ly, Neang S., Lenhard, Justin R., Holden, Patricia N., Bulitta, Jürgen B., Tsuji, Brian T.
Publicado no Antimicrob Agents Chemother (2017)

Combination Regimens of Favipiravir Plus Interferon Alpha Inhibit Chikungunya Virus Replication in Clinically Relevant Human Cell Lines

por Franco, Evelyn J., Tao, Xun, Hanrahan, Kaley C., Zhou, Jieqiang, Bulitta, Jürgen B., Brown, Ashley N.
Publicado no Microorganisms (2021)