Performance and Robustness of the Monte Carlo Importance Sampling Algorithm Using Parallelized S-ADAPT for Basic and Complex Mechanistic Models

by Bulitta, Jurgen B., Landersdorfer, Cornelia B.
Published 2011

Impact of Two-Component Regulatory Systems PhoP-PhoQ and PmrA-PmrB on Colistin Pharmacodynamics in Pseudomonas aeruginosa

by Ly, Neang S., Yang, Jenny, Bulitta, Jurgen B., Tsuji, Brian T.
Published 2012

Distinguishing Antimicrobial Models with Different Resistance Mechanisms via Population Pharmacodynamic Modeling

by Jacobs, Matthieu, Grégoire, Nicolas, Couet, William, Bulitta, Jurgen B.
Published in PLoS Comput Biol (2016)

Development of a New Pre- and Post-Processing Tool (SADAPT-TRAN) for Nonlinear Mixed-Effects Modeling in S-ADAPT

by Bulitta, Jurgen Bernd, Bingölbali, Ayhan, Shin, Beom Soo, Landersdorfer, Cornelia Barbara
Published 2011

Development and validation of a liquid chromatography - mass spectrometry assay for polymyxin B in bacterial growth media

by Cheah, Soon-Ee, Bulitta, Jurgen B., Li, Jian, Nation, Roger L.
Published 2014

Novel Rate-Area-Shape Modeling Approach To Quantify Bacterial Killing and Regrowth for In Vitro Static Time-Kill Studies

by Cheah, Soon-Ee, Li, Jian, Nation, Roger L., Bulitta, Jürgen B.
Published in Antimicrob Agents Chemother (2014)

Optimization of Synergistic Combination Regimens against Carbapenem- and Aminoglycoside-Resistant Clinical Pseudomonas aeruginosa Isolates via Mechanism-Based Pharmacokinetic/Pharm...

by Yadav, Rajbharan, Bulitta, Jürgen B., Nation, Roger L., Landersdorfer, Cornelia B.
Published in Antimicrob Agents Chemother (2016)

Quantifying Subpopulation Synergy for Antibiotic Combinations via Mechanism-Based Modeling and a Sequential Dosing Design

by Landersdorfer, Cornelia B., Ly, Neang S., Xu, Hongmei, Tsuji, Brian T., Bulitta, Jürgen B.
Published 2013

Evaluation of Pharmacokinetic/Pharmacodynamic Model-Based Optimized Combination Regimens against Multidrug-Resistant Pseudomonas aeruginosa in a Murine Thigh Infection Model by Usi...

by Yadav, Rajbharan, Bulitta, Jürgen B., Wang, Jiping, Nation, Roger L., Landersdorfer, Cornelia B.
Published in Antimicrob Agents Chemother (2017)

Novel Approach To Optimize Synergistic Carbapenem-Aminoglycoside Combinations against Carbapenem-Resistant Acinetobacter baumannii

by Yadav, Rajbharan, Landersdorfer, Cornelia B., Nation, Roger L., Boyce, John D., Bulitta, Jürgen B.
Published in Antimicrob Agents Chemother (2015)

Evaluation of Tobramycin and Ciprofloxacin as a Synergistic Combination Against Hypermutable Pseudomonas Aeruginosa Strains via Mechanism-Based Modelling

by Rees, Vanessa E., Bulitta, Jürgen B., Oliver, Antonio, Nation, Roger L., Landersdorfer, Cornelia B.
Published in Pharmaceutics (2019)

Development and Qualification of a Pharmacodynamic Model for the Pronounced Inoculum Effect of Ceftazidime against Pseudomonas aeruginosa

by Bulitta, Jürgen B., Ly, Neang S., Yang, Jenny C., Forrest, Alan, Jusko, William J., Tsuji, Brian T.
Published 2009

Modeling the Autoinhibition of Clarithromycin Metabolism during Repeated Oral Administration

by Abduljalil, Khaled, Kinzig, Martina, Bulitta, Jürgen, Horkovics-Kovats, Stefan, Sörgel, Fritz, Rodamer, Michael, Fuhr, Uwe
Published 2009

Pharmacokinetic/Pharmacodynamic Investigation of Colistin against Pseudomonas aeruginosa Using an In Vitro Model

by Bergen, Phillip J., Bulitta, Jurgen B., Forrest, Alan, Tsuji, Brian T., Li, Jian, Nation, Roger L.
Published 2010

Nonlinear pharmacokinetics of piperacillin in healthy volunteers – implications for optimal dosage regimens

by Bulitta, Jürgen B, Kinzig, Martina, Jakob, Verena, Holzgrabe, Ulrike, Sörgel, Fritz, Holford, Nicholas H G
Published 2010

Colistin and Polymyxin B Dosage Regimens against Acinetobacter baumannii: Differences in Activity and the Emergence of Resistance

by Cheah, Soon-Ee, Li, Jian, Tsuji, Brian T., Forrest, Alan, Bulitta, Jürgen B., Nation, Roger L.
Published in Antimicrob Agents Chemother (2016)

Inhibition of flucloxacillin tubular renal secretion by piperacillin

by Landersdorfer, Cornelia B, Kirkpatrick, Carl M J, Kinzig, Martina, Bulitta, Jürgen B, Holzgrabe, Ulrike, Sörgel, Fritz
Published 2008

Mechanism-Based Model of Parasite Growth and Dihydroartemisinin Pharmacodynamics in Murine Malaria

by Patel, Kashyap, Batty, Kevin T., Moore, Brioni R., Gibbons, Peter L., Bulitta, Jürgen B., Kirkpatrick, Carl M.
Published 2013

Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin

by Bulman, Zackery P., Ly, Neang S., Lenhard, Justin R., Holden, Patricia N., Bulitta, Jürgen B., Tsuji, Brian T.
Published in Antimicrob Agents Chemother (2017)

Combination Regimens of Favipiravir Plus Interferon Alpha Inhibit Chikungunya Virus Replication in Clinically Relevant Human Cell Lines

by Franco, Evelyn J., Tao, Xun, Hanrahan, Kaley C., Zhou, Jieqiang, Bulitta, Jürgen B., Brown, Ashley N.
Published in Microorganisms (2021)