POU Transcription Factors Brn-3a and Brn-3b Interact with the Estrogen Receptor and Differentially Regulate Transcriptional Activity via an Estrogen Response Element

Por Budhram-Mahadeo, Vishwanie, Parker, Malcolm, Latchman, David S.
Publicado em 1998

A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53

Por Sugars, Katharine L., Budhram-Mahadeo, Vishwanie, Packham, Graham, Latchman, David S.
Publicado em 2001

Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate.

Por Hudson, Chantelle D., Morris, Peter J., Latchman, David S., Budhram-Mahadeo, Vishwanie S.
Publicado no J Biol Chem (2015)

Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate.

Por Hudson, Chantelle D., Morris, Peter J., Latchman, David S., Budhram-Mahadeo, Vishwanie S.
Publicado no J Biol Chem (2016)

A Simple Technique for the Prediction of Interacting Proteins Reveals a Direct Brn-3a-Androgen Receptor Interaction

Por Berwick, Daniel C., Diss, James K. J., Budhram-Mahadeo, Vishwanie S., Latchman, David S.
Publicado em 2010

The Brn-3b transcription factor regulates the growth, behavior, and invasiveness of human neuroblastoma cells in vitro and in vivo.

Por Irshad, Shazia, Pedley, R. Barbara, Anderson, John, Latchman, David S., Budhram-Mahadeo, Vishwanie
Publicado no J Biol Chem (2015)

Proliferation-associated POU4F2/Brn-3b transcription factor expression is regulated by oestrogen through ERα and growth factors via MAPK pathway

Por Ounzain, Samir, Bowen, Samantha, Patel, Chandrakant, Fujita, Rieko, Heads, Richard J, Budhram-Mahadeo, Vishwanie S
Publicado em 2011

Profound hyperglycemia in knockout mutant mice identifies novel function for POU4F2/Brn-3b in regulating metabolic processes

Por Bitsi, Stavroula, Ali, Houda, Maskell, Lauren, Ounzain, Samir, Mohamed-Ali, Vidya, Budhram-Mahadeo, Vishwanie S.
Publicado no Am J Physiol Endocrinol Metab (2015)

Hsp-27 induction requires POU4F2/Brn-3b TF in doxorubicin-treated breast cancer cells, whereas phosphorylation alters its cellular localisation following drug treatment

Por Fujita, Rieko, Ounzain, Samir, Wang, Alice Chun Yin, Heads, Richard John, Budhram-Mahadeo, Vishwanie Shanie
Publicado em 2011

Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression

Por Budhram-Mahadeo, Vishwanie S., Bowen, Samantha, Lee, Sonia, Perez-Sanchez, Christina, Ensor, Elizabeth, Morris, Peter J., Latchman, David S.
Publicado em 2006

Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart

Por Maskell, Lauren J, Qamar, Kashif, Babakr, Aram A, Hawkins, Thomas A, Heads, Richard J, Budhram-Mahadeo, Vishwanie S
Publicado no Cell Death Dis (2017)

Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression

Por Farooqui-Kabir, Saleha R., Diss, James K. J., Henderson, Deborah, Marber, Michael S., Latchman, David S., Budhram-Mahadeo, Vishwanie, Heads, Richard J.
Publicado em 2008

Protein Kinase Cε-Calcineurin Cosignaling Downstream of Toll-Like Receptor 4 Downregulates Fibrosis and Induces Wound Healing Gene Expression in Cardiac Myofibroblasts

Por Mesquita, Rui F. D. S., Paul, Margaret A., Valmaseda, Aida, Francois, Asvi, Jabr, Rita, Anjum, Shahzia, Marber, Michael S., Budhram-Mahadeo, Vishwanie, Heads, Richard J.
Publicado em 2014