Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart

Congenital heart defects contribute to embryonic or neonatal lethality but due to the complexity of cardiac development, the molecular changes associated with such defects are not fully understood. Here, we report that transcription factors (TFs) Brn-3a (POU4F1) and Brn-3b (POU4F2) are important for...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Maskell, Lauren J, Qamar, Kashif, Babakr, Aram A, Hawkins, Thomas A, Heads, Richard J, Budhram-Mahadeo, Vishwanie S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520879/
https://ncbi.nlm.nih.gov/pubmed/28594399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.185
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