Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart

Congenital heart defects contribute to embryonic or neonatal lethality but due to the complexity of cardiac development, the molecular changes associated with such defects are not fully understood. Here, we report that transcription factors (TFs) Brn-3a (POU4F1) and Brn-3b (POU4F2) are important for...

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Detalles Bibliográficos
Publicado en:Cell Death Dis
Main Authors: Maskell, Lauren J, Qamar, Kashif, Babakr, Aram A, Hawkins, Thomas A, Heads, Richard J, Budhram-Mahadeo, Vishwanie S
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520879/
https://ncbi.nlm.nih.gov/pubmed/28594399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.185
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