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The POU4F2/Brn-3b transcription factor is required for the hypertrophic response to angiotensin II in the heart

Adult hearts respond to increased workload such as prolonged stress or injury, by undergoing hypertrophic growth. During this process, the early adaptive responses are important for maintaining cardiac output whereas at later stages, pathological responses such as cardiomyocyte apoptosis and fibrosi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Mele, Laura, Maskell, Lauren J., Stuckey, Daniel J., Clark, James E., Heads, Richard J., Budhram-Mahadeo, Vishwanie S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694165/
https://ncbi.nlm.nih.gov/pubmed/31413277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1848-y
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