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The POU4F2/Brn-3b transcription factor is required for the hypertrophic response to angiotensin II in the heart

Adult hearts respond to increased workload such as prolonged stress or injury, by undergoing hypertrophic growth. During this process, the early adaptive responses are important for maintaining cardiac output whereas at later stages, pathological responses such as cardiomyocyte apoptosis and fibrosi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Mele, Laura, Maskell, Lauren J., Stuckey, Daniel J., Clark, James E., Heads, Richard J., Budhram-Mahadeo, Vishwanie S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694165/
https://ncbi.nlm.nih.gov/pubmed/31413277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1848-y
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