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A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53

The Brn-3a transcription factor stimulates the expression of the anti-apoptotic Bcl-2 and Bcl-x proteins and protects neuronal cells from apoptosis. Here we show that a minimal Bcl-x promoter is activated by Brn-3a and that this stimulation is prevented by the pro-apoptotic p53 protein. Both these e...

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Autors principals: Sugars, Katharine L., Budhram-Mahadeo, Vishwanie, Packham, Graham, Latchman, David S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC92563/
https://ncbi.nlm.nih.gov/pubmed/11713302
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