A radical explanation for glucose-induced β cell dysfunction

Autor Brownlee, Michael
Vydáno 2003

Foreword

Autor Brownlee, Michael
Vydáno 2003

Hyperglycemia-Induced Reactive Oxygen Species Increase Expression of the Receptor for Advanced Glycation End Products (RAGE) and RAGE Ligands

Autor Yao, Dachun, Brownlee, Michael
Vydáno 2010

Oxidative stress and diabetic complications

Autor Giacco, Ferdinando, Brownlee, Michael
Vydáno 2010

Molecular and Cellular Mechanisms of Cardiovascular Disorders in Diabetes

Autor Shah, Manasi S., Brownlee, Michael
Vydáno v Circ Res (2016)

Mitochondrial reactive oxygen species in the pathogenesis of early diabetic nephropathy

Autor Nishikawa, Takeshi, Brownlee, Michael, Araki, Eiichi
Vydáno v J Diabetes Investig (2015)

Susceptibility to Apoptosis in Insulin-like Growth Factor-I Receptor-deficient Brown Adipocytes

Autor Valverde, Angela M., Mur, Cecilia, Brownlee, Michael, Benito, Manuel
Vydáno 2004

Diabetic Retinopathy: Targeting Vasoregression

Autor Hammes, Hans-Peter, Feng, Yuxi, Pfister, Frederick, Brownlee, Michael
Vydáno 2011

Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site

Autor Du, Xue Liang, Edelstein, Diane, Dimmeler, Stefanie, Ju, Qida, Sui, Chengyu, Brownlee, Michael
Vydáno 2001

Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation

Autor Du, Xueliang, Edelstein, Diane, Obici, Silvana, Higham, Ninon, Zou, Ming-Hui, Brownlee, Michael
Vydáno 2006

Glucagon-Like Peptide-1 Cleavage Product GLP-1(9-36) Amide Rescues Synaptic Plasticity and Memory Deficits in Alzheimer's Disease Model Mice

Autor Ma, Tao, Du, Xueliang, Pick, Joseph E., Sui, Guangzhi, Brownlee, Michael, Klann, Eric
Vydáno 2012

Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells

Autor Du, Xueliang, Matsumura, Takeshi, Edelstein, Diane, Rossetti, Luciano, Zsengellér, Zsuzsanna, Szabó, Csaba, Brownlee, Michael
Vydáno 2003

Knockdown of Glyoxalase 1 Mimics Diabetic Nephropathy in Nondiabetic Mice

Autor Giacco, Ferdinando, Du, Xueliang, D’Agati, Vivette D., Milne, Ross, Sui, Guangzhi, Geoffrion, Michele, Brownlee, Michael
Vydáno 2014

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosyl...

Autor Du, Xue-Liang, Edelstein, Diane, Rossetti, Luciano, Fantus, Ivan George, Goldberg, Howard, Ziyadeh, Fuad, Wu, Jie, Brownlee, Michael
Vydáno 2000

Decreasing Intracellular Superoxide Corrects Defective Ischemia-induced New Vessel Formation in Diabetic Mice

Autor Ceradini, Daniel J., Yao, Dachun, Grogan, Raymon H., Callaghan, Matthew J., Edelstein, Diane, Brownlee, Michael, Gurtner, Geoffrey C.
Vydáno 2008

Hyperglycemia Impairs Proteasome Function by Methylglyoxal

Autor Queisser, Markus A., Yao, Dachun, Geisler, Sven, Hammes, Hans-Peter, Lochnit, Günter, Schleicher, Erwin D., Brownlee, Michael, Preissner, Klaus T.
Vydáno 2010

Advanced glycation endproduct (AGE) accumulation and AGE receptor (RAGE) up‐regulation contribute to the onset of diabetic cardiomyopathy

Autor Ma, Heng, Li, Shi‐Yan, Xu, Peisheng, Babcock, Sara A., Dolence, E. Kurt, Brownlee, Michael, Li, Ji, Ren, Jun
Vydáno 2008

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

Autor El-Osta, Assam, Brasacchio, Daniella, Yao, Dachun, Pocai, Alessandro, Jones, Peter L., Roeder, Robert G., Cooper, Mark E., Brownlee, Michael
Vydáno 2008

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

Autor El-Osta, Assam, Brasacchio, Daniella, Yao, Dachun, Pocai, Alessandro, Jones, Peter L., Roeder, Robert G., Cooper, Mark E., Brownlee, Michael
Vydáno 2008

Persistent Oxidative Stress Due to Absence of Uncoupling Protein 2 Associated with Impaired Pancreatic β-Cell Function

Autor Pi, Jingbo, Bai, Yushi, Daniel, Kiefer W., Liu, Dianxin, Lyght, Otis, Edelstein, Diane, Brownlee, Michael, Corkey, Barbara E., Collins, Sheila
Vydáno 2009