Targeting MYC Expression through G-Quadruplexes

著者: Brooks, Tracy A., Hurley, Laurence H.
出版事項 2010

Making sense of G-quadruplex and i-motif functions in oncogene promoters

著者: Brooks, Tracy A., Kendrick, Samantha, Hurley, Laurence
出版事項 2010

Nucleic acid clamp-mediated recognition and stabilization of the physiologically relevant MYC promoter G-quadruplex

著者: Hao, Taisen, Gaerig, Vanessa C., Brooks, Tracy A.
出版年 Nucleic Acids Res (2016)

Helping Eve Overcome ADAM: G-Quadruplexes in the ADAM-15 Promoter as New Molecular Targets for Breast Cancer Therapeutics

著者: Brown, Robert V., Gaerig, Vanessa C., Simmons, Taesha, Brooks, Tracy A.
出版年 Molecules (2013)

Effect of Interior Loop Length on the Thermal Stability and pK(a) of i-Motif DNA

著者: Reilly, Samantha M., Morgan, Rhianna K., Brooks, Tracy A., Wadkins, Randy M.
出版年 Biochemistry (2015)

Demonstration that Drug-targeted Down-regulation of MYC in Non-Hodgkins Lymphoma Is Directly Mediated through the Promoter G-quadruplex

著者: Brown, Robert V., Danford, Forest L., Gokhale, Vijay, Hurley, Laurence H., Brooks, Tracy A.
出版事項 2011

Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations

著者: Brooks, Tracy A., Hawkins, Brian T., Huber, Jason D., Egleton, Richard D., Davis, Thomas P.
出版年 Am J Physiol Heart Circ Physiol (2005)

Molecular cloning of the human PDGFR-β promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-β expression

著者: Qin, Yong, Fortin, Jessica S., Tye, Denise, Gleason-Guzman, Mary, Brooks, Tracy A., Hurley, Laurence H.
出版事項 2010

Epigenetic Modification, Dehydration, and Molecular Crowding Effects on the Thermodynamics of i-Motif Structure Formation from C-Rich DNA

著者: Bhavsar-Jog, Yogini P., Van Dornshuld, Eric, Brooks, Tracy A., Tschumper, Gregory S., Wadkins, Randy M.
出版事項 2014

Co-Localization of DNA i-Motif-Forming Sequences and 5-Hydroxymethyl-cytosines in Human Embryonic Stem Cells

著者: Bhavsar-Jog, Yogini P., Van Dornshuld, Eric, Brooks, Tracy A., Tschumper, Gregory S., Wadkins, Randy M.
出版年 Molecules (2019)

Effects of 5-Hydroxymethylcytosine Epigenetic Modification on the Stability and Molecular Recognition of VEGF i-Motif and G-Quadruplex Structures

著者: Morgan, Rhianna K., Molnar, Michael M., Batra, Harshul, Summerford, Bethany, Wadkins, Randy M., Brooks, Tracy A.
出版年 J Nucleic Acids (2018)

The anticancer activity and cellular repression of c-MYC by the G-quadruplex-stabilizing 11-piperazinyl quindoline is not dependent on direct targeting of the G-quadruplex in the c...

著者: Boddupally, Peda V. L., Hahn, Seongmin, Beman, Cristina, De, Biswanath, Brooks, Tracy A., Gokhale, Vijay, Hurley, Laurence H.
出版事項 2012

Biphasic cytoarchitecture and functional changes in the BBB induced by chronic inflammatory pain

著者: Brooks, Tracy A., Ocheltree, Scott M., Seelbach, Melissa J., Charles, Rachael A., Nametz, Nicole, Egleton, Richard D., Davis, Thomas P.
出版事項 2006

Occludin oligomeric assembly at tight junctions of the blood-brain barrier is disrupted by peripheral inflammatory hyperalgesia

著者: McCaffrey, Gwen, Seelbach, Melissa J., Staatz, William D., Nametz, Nicole, Quigley, Carolyn, Campos, Chris R., Brooks, Tracy A., Davis, Thomas P.
出版事項 2008

Increased MYC gene copy number correlates with increased mRNA levels in diffuse large B-cell lymphoma

著者: Stasik, Christopher J., Nitta, Hiroaki, Zhang, Wenjun, Mosher, Charles H., Cook, James R., Tubbs, Raymond R., Unger, Joseph M., Brooks, Tracy A., Persky, Daniel O., Wilkinson, Sarah T., Grogan, Thomas M., Rimsza, Lisa M.
出版事項 2010