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Molecular cloning of the human PDGFR-β promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-β expression
To understand the mechanisms controlling platelet-derived growth factor receptor β (PDGFR-β) expression in malignancies, we have cloned and characterized the first functional promoter of the human PDGFR-β gene, which has been confirmed by luciferase reporter gene assays. The transcription initiation...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2868086/ https://ncbi.nlm.nih.gov/pubmed/20377208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100330w |
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